New chlorinated metabolites from the tropical marine sponge Dysidea herbacea

被引：31
|
作者：
Dumdei, EJ [1 ]
Simpson, JS [1 ]
Garson, MJ [1 ]
Byriel, KA [1 ]
Kennard, CHL [1 ]
机构：
[1] UNIV QUEENSLAND, DEPT CHEM, BRISBANE, QLD 4072, AUSTRALIA
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 1997年 / 50卷 / 02期
基金：
澳大利亚研究理事会;
关键词：
D O I：
10.1071/C96111
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three new chlorinated metabolites, namely 3-(3,3-dichloro-2-methylpropyl)-6-(3,3-dichloro-2-methylpropylidene)-1,4-dimethylpiperazine-2,5-dione (3), 1-methyl-3-(3,3,3-trichloro-2-methylpropyl)-6-(3,3,3-trichloro-2-methylpropylidene)piperazine-2,5-dione (4) and 5,5-dichloro-4-methyl-2-[methyl(4,4-dichloro-3-methyl-1-oxobutyl)amino]-N-(thiazol-2-ylmethyl)pentanamide (8), have been isolated from collections of Dysidea herbacea from the southern region of the Great Barrier Reef. The relative and absolute stereochemistry of (4) was determined by X-ray crystallographic analysis.
引用
收藏
页码：139 / 144
页数：6
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