Three new lanostanoid triterpenes from the fruiting bodies of Ganoderma tropicum

被引：28

作者：

Hu, Li-Li ^{[1
,2
]}

Ma, Qing-Yun ^{[1
]}

Huang, Sheng-Zhuo ^{[1
]}

Guo, Zhi-Kai ^{[1
]}

Ma, Hai-Xia ^{[1
]}

Guo, Jian-Chun ^{[1
]}

Dai, Hao-Fu ^{[1
]}

Zhao, You-Xing ^{[1
]}

机构：

[1] CATAS, MOA Key Lab Trop Crop Biol & Genet Resources Util, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

[2] Hainan Univ, Coll Agr, Haikou 570228, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2013年 / 15卷 / 04期

关键词：

Ganoderma tropicum; Ganodermataceae; lanostanoid triterpene; AChE inhibitory activity; LUCIDUM; INHIBITION; EXTRACT;

D O I：

10.1080/10286020.2013.764869

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new lanostanoid triterpenes, 3,7,15-trihydroxy-11,23-dioxo-lanost-8,16-dien-26-oic acid (1), 3,7,15-trihydroxy-11,23-dioxo-lanost-8,16-dien-26-oic acid methyl ester (2), and 3,15-dihydroxy-7,11,23-trioxo-lanost-8,16-dien-26-oic acid methyl ester (3) were isolated from the EtOAc extract of the fruiting bodies of Ganoderma tropicum. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) of these isolates was evaluated and compound 2 exhibited definite inhibitory activity against AChE.

引用

页码：357 / 362

页数：6

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