A novel and facile synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones via a one-pot multi-component reaction

被引：69
|
作者：
Heravi, Majid M. [1 ]
Baghernejad, Bita [1 ]
Oskooie, Hossein A. [1 ]
Hekmatshoar, Rahim [1 ]
机构：
[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2008年 / 49卷 / 42期
关键词：
cyclohexyl isocyanide; 1,3-dicarbonyl compound; multi-component reaction; 1H-indole-4(5H)-ones;
D O I：
10.1016/j.tetlet.2008.08.012
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones was achieved via a one-pot multi-component reaction of cyclohexyl isocyanide, an aldehyde, a 1,3-dicarbonyl compound, and ammonium acetate in the presence of a catalytic amount of KHSO4 in acetonitrile. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6101 / 6103
页数：3
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