The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

被引：276

作者：

Koolhaas, Jaap M. ^{[1
]}

Coppens, Caroline M. ^{[1
]}

de Boer, Sietse F. ^{[1
]}

Buwalda, Bauke ^{[1
]}

Meerlo, Peter ^{[1
]}

Timmermans, Paul J. A. ^{[2
]}

机构：

[1] Univ Groningen, Dept Behav Physiol, Ctr Behav & Neurosci, NL-9700 AB Groningen, Netherlands

[2] Radboud Univ Nijmegen, NL-6525 ED Nijmegen, Netherlands

来源：

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS | 2013年 / 77期

关键词：

Behavior; Issue; 77; Neuroscience; Medicine; Anatomy; Physiology; Genetics; Basic Protocols; Psychology; offensive aggression; defensive behavior; aggressive behavior; pathological; violence; social stress; rat; Wistar rat; animal model;

D O I：

10.3791/4367

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This video publication explains in detail the experimental protocol of the resident-intruder paradigm in rats. This test is a standardized method to measure offensive aggression and defensive behavior in a semi natural setting. The most important behavioral elements performed by the resident and the intruder are demonstrated in the video and illustrated using artistic drawings. The use of the resident intruder paradigm for acute and chronic social stress experiments is explained as well. Finally, some brief tests and criteria are presented to distinguish aggression from its more violent and pathological forms.

引用

页数：7

共 46 条

[21] EFFECT OF SOCIAL-HOUSING CONDITIONS ON AGGRESSION IN AN INTRUDER-RESIDENT PARADIGM IN CAVIA-PORCELLUS
GEISSLER, KR
MELVIN, KB
PSYCHOLOGICAL RECORD, 1977, 27 (03): : 537 - 543
[22] Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test
Silva, Epifanio F.
Silva, Aldemara I.
Asth, Laila
Souza, Lisiane S.
Zaveri, Nurulain T.
Guerrini, Remo
Calo', Girolamo
Ruzza, Chiara
Gavioli, Elaine C.
BEHAVIOURAL BRAIN RESEARCH, 2019, 356 : 120 - 126
[23] Individual differences in behaviour: A test of 'coping style' does not predict resident-intruder aggressiveness in pigs
D'Eath, RB
Burn, CC
BEHAVIOUR, 2002, 139 : 1175 - 1194
[24] AGGRESSIVE BEHAVIORS IN THE LITHIUM-PILOCARPINE RAT MODELS OF TEMPORAL LOBE EPILEPSY: RESIDENT-INTRUDER TEST
Jeon, D-J
Bae, E-G
Jung, K-H
Chu, K.
Lee, S. K.
EPILEPSIA, 2009, 50 : 98 - 98
[25] Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident-intruder paradigm in rats
Trent, Simon
Drew, Cheney J. G.
Mitchell, Paul J.
Bailey, Sarah J.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2009, 19 (12) : 876 - 886
[26] The Effects of Social Hierarchy Establishment in Resident-Intruder Model on Testicular Function in Laboratory Mice of Different Inbred Strains
Kleshchev, M. A.
Osadchuk, A. V.
Osadchuk, L. V.
JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY, 2023, 59 (04) : 1426 - 1437
[27] Facilitation of hypothalamic-pituitary-adrenal responses to novel stress following repeated social stress using the resident/intruder paradigm
Bhatnagar, S
Vining, C
HORMONES AND BEHAVIOR, 2003, 43 (01) : 158 - 165
[28] The Effects of Social Hierarchy Establishment in Resident-Intruder Model on Testicular Function in Laboratory Mice of Different Inbred Strains
M. A. Kleshchev
A. V. Osadchuk
L. V. Osadchuk
Journal of Evolutionary Biochemistry and Physiology, 2023, 59 : 1426 - 1437
[29] Resident intruder paradigm-induced aggression relieves depressive-like behaviors in male rats subjected to chronic mild stress
Wei, Sheng
Ji, Xiao-wei
Wu, Chun-ling
Li, Zi-fa
Sun, Peng
Wang, Jie-qiong
Zhao, Qi-tao
Gao, Jie
Guo, Ying-hui
Sun, Shi-guang
Qiao, Ming-qi
MEDICAL SCIENCE MONITOR, 2014, 20 : 945 - 952
[30] Individual aggressiveness measured in a resident-intruder test predicts the persistence of aggressive behaviour and weight gain of young pigs after mixing
D'Eath, RB
APPLIED ANIMAL BEHAVIOUR SCIENCE, 2002, 77 (04) : 267 - 283

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