Geldanamycin Induces Motor Neuron Apoptosis by Inhibition of the PI3K/AKT Pathway

被引:0
|
作者
Dennys, C. N. [1 ]
Gitto, S. [1 ]
Franco, M. [1 ]
Estevez, A. [1 ]
Strayer, A. [2 ]
机构
[1] Univ Cent Florida, Burnett Sch Biomed Sci, Coll Med, Orlando, FL 32816 USA
[2] Weill Cornell Med Coll, Dept Neurol & Neurosci, New York, NY USA
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
1463
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Cadmium induces apoptosis and autophagy in swine small intestine by downregulating the PI3K/Akt pathway
    Zhang, Haoran
    Huang, Jiaqiang
    Yang, Jie
    Cai, Jingzeng
    Liu, Qi
    Zhang, Xintong
    Bao, Jun
    Zhang, Ziwei
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2022, 29 (27) : 41207 - 41218
  • [22] Honokiol induces autophagy and apoptosis of osteosarcoma through PI3K/Akt/mTOR signaling pathway
    Li, Zhiquan
    Dong, Hui
    Li, Mo
    Wu, Yaoping
    Liu, Yanwu
    Zhao, Yinan
    Chen, Xiaochao
    Ma, Minliang
    MOLECULAR MEDICINE REPORTS, 2018, 17 (02) : 2719 - 2723
  • [23] Combined inhibition of CDK and PI3K/Akt pathways induces apoptosis of mantle cell lymphoma
    Mohapatra, Subhra
    Chu, Baoky
    Zhao, Xiuhua
    Tao, Jianguo
    Sotomayor, Eduardo
    Pledger, W. Jack
    BLOOD, 2007, 110 (11) : 416A - 416A
  • [24] PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway
    Liu, Shen
    Jia, Jun
    Zhou, Hengxing
    Zhang, Chi
    Liu, Lu
    Liu, Jun
    Lu, Lu
    Li, Xueying
    Kang, Yi
    Lou, Yongfu
    Cai, Zhiwei
    Ren, Yiming
    Kong, Xiaohong
    Feng, Shiqing
    MOLECULAR MEDICINE REPORTS, 2019, 20 (05) : 4059 - 4066
  • [25] PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signalling pathway
    Liu, L.
    Zhou, H.
    Li, X.
    Liu, S.
    Lu, L.
    Liu, J.
    Kang, Y.
    Cai, Z.
    Lou, Y.
    Zhang, C.
    Qi, Z.
    Jian, H.
    Feng, S.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 627 - 627
  • [26] Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors
    LoRusso, Patricia Mucci
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (31) : 3803 - +
  • [27] Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis
    Barra, Fabio
    Desideri, Lorenzo Ferro
    Ferrero, Simone
    BRITISH JOURNAL OF PHARMACOLOGY, 2018, 175 (17) : 3626 - 3627
  • [28] PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells
    Yong Choi
    Jie Zhang
    Cristina Murga
    Hong Yu
    Erich Koller
    Brett P Monia
    J Silvio Gutkind
    Weiqun Li
    Oncogene, 2002, 21 : 5289 - 5300
  • [29] PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells
    Choi, Y
    Zhang, J
    Murga, C
    Yu, H
    Koller, E
    Monia, BP
    Gutkind, JS
    Li, WQ
    ONCOGENE, 2002, 21 (34) : 5289 - 5300
  • [30] Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway
    Zhang, Yong
    Sun, Siguo
    Chen, Jun
    Ren, Pengcheng
    Hu, Yunsheng
    Cao, Zhuo
    Sun, Honghui
    Ding, Yong
    TUMOR BIOLOGY, 2014, 35 (02) : 1619 - 1625