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Evaluation and management of acute radiation dermatitis
被引:7
|作者:
Modesto, A.
[2
]
Faivre, J. -C.
[3
]
Granel-Brocard, F.
[4
]
TaoD, Y. -G.
[5
]
Pointreau, Y.
[1
,6
,7
,8
]
机构:
[1] CHRU Tours, Ctr Reg Univ Cancerol Henry S Kaplan, Serv Radiotherapie, Hop Bretonneau, F-37044 Tours, France
[2] Inst Claudius Regaud, Dept Radiotherapie, F-31000 Toulouse, France
[3] CRLCC Lorraine Alexis Vautrin, Dept Radiotherapie, F-54511 Vandoeuvre Les Nancy, France
[4] CHU Nancy, Dept Dermatol, F-54500 Vandoeuvre Les Nancy, France
[5] Inst Gustave Roussy, Dept Radiotherapie, F-94805 Villejuif, France
[6] Univ Tours, UMR Genet Immunotherapie Chim & Canc 7292, F-37000 Tours, France
[7] CNRS, UMR Genet Immunotherapie Chim & Canc 7292, F-37000 Tours, France
[8] CHRU Tours, Lab Pharmacol Toxicol, F-37000 Tours, France
来源:
关键词:
Radiotherapy;
Adverse effect;
Radiodermatitis;
Cetuximab;
Folliculitis;
SQUAMOUS-CELL CARCINOMA;
BREAST-CANCER PATIENTS;
INDUCED SKIN TOXICITY;
RANDOMIZED PHASE-III;
DOUBLE-BLIND;
ADJUVANT RADIOTHERAPY;
PROPHYLACTIC AGENT;
SUCRALFATE CREAM;
HYALURONIC-ACID;
THERAPY;
D O I:
10.1016/j.canrad.2012.05.007
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Acute radiation dermatitis remains one of the most commonly observed side effect during radiation therapy leading to complication such as superinfection or treatment disruption. Its management is characterized by a great heterogeneity. Few strategies have demonstrated a benefit in preventing radiation dermatitis, which relies mostly on decreasing dose delivered to the skin and skin care practices. Simple emollients and use of topical steroids can be useful in early stages. The singularity of the skin toxicity seen with cetuximab and radiotherapy warrants a specific grading system and distinctive clinical treatment with use of antibiotics. (c) 2012 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
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页码:456 / 461
页数:6
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