The ETS transcription factor ERG induces transcription of the Polycomb group protein EZH2 and epigenetic silencing of the tumor suppressor gene NKX3.1 in prostate cancer

被引:0
|
作者
Kunderfranco, Paolo
Grand, Maurizia Mello
Mensah, Afua
Chiorino, Giovanna
Catapano, Carlo
Carbone, Giuseppina
机构
[1] Oncol Inst Southern Switzerland IOSI, Bellinzona, Switzerland
[2] Fondo Edo Tempia, Biella, Italy
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3811
引用
收藏
页数:1
相关论文
共 47 条
  • [21] Survival of skin cancer tumor initiating cells requires the Ezh2 polycomb group protein
    Adhikary, Gautam
    Grun, Dan
    Kerr, Candace
    Balasubramanian, Sivaprakasam
    Rorke, Ellen
    Xu, Wen
    Eckert, Richard
    CANCER RESEARCH, 2015, 75
  • [22] Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer
    R Cangemi
    A Mensah
    V Albertini
    A Jain
    M Mello-Grand
    G Chiorino
    C V Catapano
    G M Carbone
    Oncogene, 2008, 27 : 2877 - 2885
  • [23] Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer
    Cangemi, R.
    Mensah, A.
    Albertini, V.
    Jain, A.
    Mello-Grand, M.
    Chiorino, G.
    Catapano, C. V.
    Carbone, G. M.
    ONCOGENE, 2008, 27 (20) : 2877 - 2885
  • [24] Oncogenic ETS transcription factors avoid repression by EZH2 and FOXO1 in prostate cancer and Ewing sarcoma
    Downing, Nicholas F.
    Mills, Kaitlyn M.
    Hollenhorst, Peter C.
    CANCER RESEARCH, 2024, 84 (06)
  • [25] Determination of molecular patterns associated with the expression of the TMPRSS2-ERG fusion and ERG, EZH2, NKX3.1 and SPINK-1 genes to evaluate the clonal origin of multifocal prostate cancer and its association with disease progression.
    Segura Moreno, Yenifer Yamile
    Sanabria Salas, Maria Carolina
    Mesa Lopez De Mesa, Jorge Andres
    Varela Ramirez, Rodolfo
    Acosta Vega, Natalia Lizeth
    Lucia Serrano, Martha
    CANCER RESEARCH, 2021, 81 (13)
  • [26] A new kinetochore component CENP-W interacts with the polycomb-group protein EZH2 to promote gene silencing
    Koh, Wansoo
    Park, Byoungwoo
    Lee, Soojin
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 464 (01) : 256 - 262
  • [27] Repression of Id4 (inhibitor of DNA binding 4) by the polycomb group protein EZH2 in prostate cancer
    Chinaranagari, Swathi
    Sharma, Pankaj
    Chaudhary, Jaideep
    CANCER RESEARCH, 2013, 73
  • [28] Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation
    Kedage, Vivekananda
    Strittmatter, Brady G.
    Dausinas, Paige B.
    Hollenhorst, Peter C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (42) : 17225 - 17235
  • [29] Relation of ETS transcription factor family member ERG, androgen receptor and topoisomerase 2β expression to TMPRSS2-ERG fusion status in prostate cancer
    Kolar, Z.
    Burdova, A.
    Jamaspishvili, T.
    Bouchal, J.
    Kucerova, R.
    Bienova, M.
    Kral, M.
    Student, V.
    NEOPLASMA, 2014, 61 (01) : 9 - 16
  • [30] The polycomb group protein EZH2 induces epithelial–mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter
    Lu Gan
    Midie Xu
    Ruixi Hua
    Cong Tan
    Jieyun Zhang
    Yiwei Gong
    Zhenhua Wu
    Weiwei Weng
    Weiqi Sheng
    Weijian Guo
    Journal of Hematology & Oncology, 11