OLD WORLD LEISHMANIA INFANTUM CUTANEOUS LEISHMANIASIS UNRESPONSIVE TO LIPOSOMAL AMPHOTERICIN B TREATED WITH TOPICAL IMIQUIMOD

被引:22
|
作者
Hervas, Juan A. [1 ,2 ]
Martin-Santiago, Ana [3 ]
Hervas, Daniel [2 ]
Rojo, Estrella [4 ]
Mena, Ana [4 ]
Rocamora, Vicente [3 ]
Duenas, Joaquin [1 ]
机构
[1] Son Espases Univ Hosp, Sect Pediat Infect Dis, Palma De Mallorca 07010, The Balearic Is, Spain
[2] Son Espases Univ Hosp, IUNICS, Palma De Mallorca 07010, The Balearic Is, Spain
[3] Son Espases Univ Hosp, Dept Dermatol, Palma De Mallorca 07010, The Balearic Is, Spain
[4] Son Espases Univ Hosp, Dept Clin Microbiol, Palma De Mallorca 07010, The Balearic Is, Spain
关键词
cutaneous leishmaniasis; Leishmania infantum; liposomal amphotericin B; imiquimod; treatment failure; INFECTION; BRAZILIENSIS; RESISTANCE;
D O I
10.1097/INF.0b013e31822dfbf7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the literature on the treatment failure of liposomal amphotericin B for cutaneous leishmaniasis.
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页码:97 / 100
页数:5
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