Laser enhanced high-intensity focused ultrasound thrombolysis: An in vitro study

被引：24
|
作者：
Cui, Huizhong [1 ]
Yang, Xinmai [1 ]
机构：
[1] Univ Kansas, Dept Mech Engn, KU Bioengn Res Ctr, Lawrence, KS 66045 USA
来源：
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA | 2013年 / 133卷 / 02期
关键词：
CATHETER-DIRECTED THROMBOLYSIS; DEEP VENOUS THROMBOSIS; ACCELERATED THROMBOLYSIS; FIBRINOLYSIS; CAVITATION; EFFICACY; SAFETY; TUMORS;
D O I：
10.1121/1.4778375
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Laser-enhanced thrombolysis by high intensity focused ultrasound (HIFU) treatment was studied in vitro with bovine blood clots. To achieve laser-enhanced thrombolysis, laser light was employed to illuminate the sample concurrently with HIFU radiation, and ultrasound and laser parameters were optimized to achieve better thrombolysis efficiency. The results indicated that the thrombolysis efficiency increased when pulse length of HIFU wave, HIFU pressure, or laser fluence increases. Also, with the presence of laser, an enhanced effect of thrombolysis was observed. (C) 2013 Acoustical Society of America
引用
收藏
页码：EL123 / EL128
页数：6
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