Teaching old drugs new tricks

被引:0
|
作者
Faille, Alexandre [1 ]
Warren, Alan J. [2 ,3 ]
机构
[1] Univ Cambridge, Cambridge Inst Med Res, Cambridge, England
[2] Univ Cambridge, Dept Haematol, Cambridge, England
[3] Univ Cambridge, Wellcome Trust Med Res Council Stem Cell Inst, Cambridge, England
来源
ELIFE | 2022年 / 11卷
关键词
mitochondria; mitoribosome; antibiotics; bacteria; Fe-S cluster; ototoxicity; Human;
D O I
10.7554/eLife.84702
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Understanding the mechanism by which streptomycin binds to the small subunit of the mitoribosome may help researchers design less toxic derivatives of this antibiotic.
引用
收藏
页数:3
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