P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) restrict the brain penetration of the Janus family of tyrosine kinase (JAK) inhibitor CYT387

被引:0
|
作者
Durmus, Selvi [1 ]
Xu, Ning [2 ]
Sparidans, Rolf W. [3 ]
Wagenaar, Els [1 ]
Beijnen, Jos H. [4 ]
Schinkel, Alfred H. [1 ]
机构
[1] Netherlands Canc Inst, Div Mol Oncol, Amsterdam, Netherlands
[2] China Japan Union Hosp, Changchun, Peoples R China
[3] Univ Utrecht, Fac Sci, Dept Pharmaceut Sci, Utrecht, Netherlands
[4] Slotervaart Hosp, Dept Pharm & Pharmacol, Amsterdam, Netherlands
来源
FASEB JOURNAL | 2013年 / 27卷
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1103.1
引用
收藏
页数:1
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