Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond

被引：10
|
作者：
Ponnatapura, Janardhana [1 ,2 ]
Kielar, Ania [3 ,4 ]
Burke, Lauren M. B. [5 ]
Lockhart, Mark E. [6 ]
Abualruz, Abdul-Rahman [1 ,2 ]
Tappouni, Rafel [1 ,2 ]
Lalwani, Neeraj [1 ,2 ]
机构：
[1] Wake Forest Univ, Med Ctr Blvd, Winston Salem, NC 27157 USA
[2] Baptist Hlth, Med Ctr Blvd, Winston Salem, NC 27157 USA
[3] Univ Ottawa, Ottawa, ON, Canada
[4] Univ Toronto, Toronto, ON, Canada
[5] Univ N Carolina, Chapel Hill, NC 27515 USA
[6] Univ Alabama Birmingham, Birmingham, AL USA
来源：
MAGNETIC RESONANCE IMAGING | 2019年 / 60卷
关键词：
Hepatic adenoma; Oral contraceptive pills and estrogen; Budd-Chiari syndrome; Peliosis; Inflammatory; HNF-1; alpha-mutated; beta-Catenin-mutated and unclassified; FOCAL NODULAR HYPERPLASIA; GENERALIZED PELIOSIS HEPATIS; BUDD-CHIARI-SYNDROME; LONG-TERM USE; HEPATOCELLULAR ADENOMA; LIVER ADENOMATOSIS; IMAGING FEATURES; MALIGNANT-TRANSFORMATION; CLASSIFICATION; MANAGEMENT;
D O I：
10.1016/j.mri.2019.04.010
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Hepatic complications of oral contraceptive pills and exogenous estrogens include intrahepatic canalicular cholestasis, neoplasm formation and vascular pathologies. While it remains controversial as to whether estrogen plays a role in focal nodular hyperplasia, hemangioma or hamartoma, exposure to oral contraceptive pills and estrogen has a strong association with hepatic adenomas. Four different subgroups of adenomas have been described: Inflammatory, HNF-1 alpha-mutated, beta-catenin-mutated and unclassified. Vascular complications may include Budd-Chiari syndrome, vascular thrombosis, dilated sinusoids and peliosis.
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页码：110 / 121
页数：12
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