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- [21] Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 studyLANCET ONCOLOGY, 2015, 16 (09): : 1133 - 1142Reid, Tony论文数: 0 引用数: 0 h-index: 0机构: Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USA Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAOronsky, Bryan论文数: 0 引用数: 0 h-index: 0机构: EpicentRx, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAScicinski, Jan论文数: 0 引用数: 0 h-index: 0机构: EpicentRx, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAScribner, Curt L.论文数: 0 引用数: 0 h-index: 0机构: RRD Int, Rockville, MD USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAKnox, Susan J.论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Dept Radiat Oncol, Stanford, CA 94305 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USANing, Shoucheng论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Dept Radiat Oncol, Stanford, CA 94305 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAPeehl, Donna M.论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Dept Urol, Stanford, CA 94305 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAKorn, Ron论文数: 0 引用数: 0 h-index: 0机构: Imaging Endpoints, Scottsdale, AZ USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAStirn, Meaghan论文数: 0 引用数: 0 h-index: 0机构: EpicentRx, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USACarter, Corey A.论文数: 0 引用数: 0 h-index: 0机构: Walter Reed Natl Mil Med Ctr, Bethesda, MD USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAOronsky, Arnold论文数: 0 引用数: 0 h-index: 0机构: InterWest Partners, Menlo Pk, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USATaylor, Michael J.论文数: 0 引用数: 0 h-index: 0机构: NonClin Safety Assessment, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAFitch, William L.论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Sch Med, Stanford, CA 94305 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USACabrales, Pedro论文数: 0 引用数: 0 h-index: 0机构: Univ Calif San Diego, Dept Bioengn, San Diego, CA 92103 USA Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAKim, Michelle M.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USABurris, Howard A.论文数: 0 引用数: 0 h-index: 0机构: Sarah Cannon Res Inst, Tennessee Oncol, Nashville, TN USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USALao, Christopher D.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAAbrouk, Nacer E. D.论文数: 0 引用数: 0 h-index: 0机构: Innovexe, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAFanger, Gary R.论文数: 0 引用数: 0 h-index: 0机构: EpicentRx, Mountain View, CA USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USAInfante, Jeffrey R.论文数: 0 引用数: 0 h-index: 0机构: Sarah Cannon Res Inst, Tennessee Oncol, Nashville, TN USA Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USA
- [22] A phase I, dose-escalation, safety, pharmacokinetic, pharmacodynamic study of thioureidobutyronitrile, a novel p53 targeted therapy, in patients with advanced solid tumors.JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)Shapiro, Geoffrey论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USASupko, Jeffrey G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USACho, Daniel C.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAHilton, John Frederick论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAHadfield, Matthew论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAPruitt-Thompson, Salida论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USABordoli-Trachsela, Eveline论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAZvereva, Nela论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAWolanski, Andrew论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USASato-DiLorenzo, Aya论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAGotthardt, Susan论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAFox, Edward A.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAVerselis, Sigitas Jonas论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAKumar, Ashok论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAHolden, Sylvia A.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USARam, Siya论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAChafai-Fadela, Karima论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAHarding, Kimberly论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAMenon, Krishna E.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USA
- [23] A phase I, open-label, dose-escalation study of the novel oral proteasome inhibitor (PI) ONX 0912 in patients with advanced refractory or recurrent solid tumors.JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)Papadopoulos, K. P.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAMendelson, D. S.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USATolcher, A. W.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAPatnaik, A.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USABurris, H. A.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USARasco, D. W.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USABendell, J. C.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAGordon, M. S.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAKato, G.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAWong, H.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USABomba, D.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USALee, S.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAGillenwater, H. H.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAWoo, T.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USAInfante, J. R.论文数: 0 引用数: 0 h-index: 0机构: South Texas Accelerated Res Therapeut START Ctr C, San Antonio, TX USA
- [24] First-in-human Phase I dose-escalation study of a MET/AXL/FGFR inhibitor, S 49076, in patients with advanced solid tumors.MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)Hollebecque, Antoine论文数: 0 引用数: 0 h-index: 0机构: Inst Cancerol Gustave Roussy, Villejuif, France Inst Cancerol Gustave Roussy, Villejuif, FranceSoria, Jean-Charles论文数: 0 引用数: 0 h-index: 0机构: Inst Cancerol Gustave Roussy, Villejuif, France Inst Cancerol Gustave Roussy, Villejuif, FranceBahleda, Ratislav论文数: 0 引用数: 0 h-index: 0机构: Inst Cancerol Gustave Roussy, Villejuif, France Inst Cancerol Gustave Roussy, Villejuif, FranceLopez-Busto, Natividad论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Int Servier, Suresnes, France Inst Cancerol Gustave Roussy, Villejuif, FranceJacquet-Bescond, Anne论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Int Servier, Suresnes, France Inst Cancerol Gustave Roussy, Villejuif, FranceBurbridge, Mike F.论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Servier, Croissy Sur Seine, France Inst Cancerol Gustave Roussy, Villejuif, FranceValerie, Cattan论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Int Servier, Suresnes, France Inst Cancerol Gustave Roussy, Villejuif, FrancePauly, Jeanne论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Int Servier, Suresnes, France Inst Cancerol Gustave Roussy, Villejuif, FranceHerranz, Maria论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Barcelona, Spain Inst Cancerol Gustave Roussy, Villejuif, FranceAzaro, Analia论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Barcelona, Spain Inst Cancerol Gustave Roussy, Villejuif, FranceDepil, Stephane论文数: 0 引用数: 0 h-index: 0机构: Inst Rech Int Servier, Suresnes, France Inst Cancerol Gustave Roussy, Villejuif, FranceRodon, Jordi论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Barcelona, Spain Inst Cancerol Gustave Roussy, Villejuif, France
- [25] First-in-human, phase 1, open-label, dose-escalation, dose-expansion study of ADCT901 as monotherapy in patients with select advanced solid tumorsJOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)Harvey, R. Donald论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USAFalchook, Gerald Steven论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USANaqash, Abdul Rafeh论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USAKim, Joseph W.论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USADowlati, Afshin论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USALe Bruchec, Yvan论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USACoudert, Isabelle论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USAErvin-Haynes, Annette L.论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USASommerhalder, David论文数: 0 引用数: 0 h-index: 0机构: Winship Canc Inst, Atlanta, GA USA
- [26] First-in-human, open-label dose-escalation and dose-expansion study of the safety, pharmacokinetics, and antitumor effects of an oral ALK inhibitor ASP3026 in patients with advanced solid tumorsJournal of Hematology & Oncology, 9Tianhong Li论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyPatricia LoRusso论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyMichael L. Maitland论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologySai-Hong Ignatius Ou论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyErkut Bahceci论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyHoward A. Ball论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyJung Wook Park论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyGeoffrey Yuen论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/OncologyAnthony Tolcher论文数: 0 引用数: 0 h-index: 0机构: University of California Davis Comprehensive Cancer Center,Division of Hematology/Oncology
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- [29] A Phase I First-in-Human Pharmacokinetic and Pharmacodynamic Study of Serdemetan in Patients with Advanced Solid TumorsCLINICAL CANCER RESEARCH, 2011, 17 (19) : 6313 - 6321Tabernero, Josep论文数: 0 引用数: 0 h-index: 0机构: Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, Spain Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainDirix, Luc论文数: 0 引用数: 0 h-index: 0机构: Sint Augustinus, Antwerp, Belgium Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainSchoffski, Patrick论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Leuven, Dept Gen Med Oncol, Louvain, Belgium Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainCervantes, Andres论文数: 0 引用数: 0 h-index: 0机构: Univ Valencia, INCLIVA, Hosp Clin, Dept Hematol & Med Oncol, Valencia, Spain Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainAntonio Lopez-Martin, Jose论文数: 0 引用数: 0 h-index: 0机构: Hosp Univ 12 Octubre, Madrid, Spain Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainCapdevila, Jaume论文数: 0 引用数: 0 h-index: 0机构: Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, Spain Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, Spainvan Beijsterveldt, Ludy论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainPlatero, Suso论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainHall, Brett论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainYuan, Zhilong论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainKnoblauch, Roland论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, SpainZhuang, Sen Hong论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev LLC, Raritan, NJ USA Univ Autonoma Barcelona, Vall dHebron Univ Hosp, Barcelona 08035, Spain
- [30] A phase I dose-escalation and PK study of continuous oral rucaparib in patients with advanced solid tumors.JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)Kristeleit, Rebecca Sophie论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandShapiro, Geoffrey论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandLoRusso, Patricia论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandInfante, Jeffrey R.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandFlynn, Michael论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandPatel, Manish R.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandTolaney, Sara M.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandHilton, John Frederick论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandCalvert, Alan Hilary论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandGiordano, Heidi论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandIsaacson, Jeffrey D.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandBorrow, Jennifer论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandAllen, Andrew R.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandJaw-Tsai, Sarah S.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, EnglandBurris, Howard A.论文数: 0 引用数: 0 h-index: 0机构: UCL, London, England