The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?

被引：58
|
作者：
Simon, Yvette [1 ]
Kessler, Sonja M. [1 ,2 ]
Bohle, Rainer M. [3 ]
Haybaeck, Johannes [2 ]
Kiemer, Alexandra K. [1 ]
机构：
[1] Univ Saarland, Dept Pharm, D-66041 Saarbrucken, Germany
[2] Med Univ Graz, Inst Pathol, Graz, Austria
[3] Univ Saarland, Dept Pathol, Homburg, Germany
来源：
GUT | 2014年 / 63卷 / 05期
关键词：
HEPATOCELLULAR-CARCINOMA; IL-13;
D O I：
10.1136/gutjnl-2013-305736
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：861 / +
页数：3
相关论文
共 50 条
  • [41] THE ROLE OF INSULIN-LIKE GROWTH FACTOR 2 BINDING PROTEIN 3 (IGF2BP3) AS A DRIVER OF TUMORIGENESIS IN GLIOBLASTOMA
    Chow, Jocelyn
    Chen, Alexander
    Oh, Se-yeong
    Young, Elizabeth
    Boyd, Nathaniel
    Read, Renee
    NEURO-ONCOLOGY, 2023, 25
  • [42] MODULATION OF GLIOMA GROWTH AND MIGRATION BY INSULIN-LIKE GROWTH-FACTOR (IGF) AND IGF BINDING PROTEIN-2 (IGFBP-2)
    MORFORD, LA
    BOGHAERT, ER
    BROOKS, WH
    ROSZMAN, TL
    FASEB JOURNAL, 1995, 9 (03): : 133 - 133
  • [43] Targeting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in metastatic melanoma to increase efficacy of BRAFV600E inhibitors
    Kim, TaeWon
    Havighurst, Thomas
    Kim, KyungMann
    Albertini, Mark
    Xu, Yaohui G.
    Spiegelman, Vladimir S.
    MOLECULAR CARCINOGENESIS, 2018, 57 (05) : 678 - 683
  • [44] Insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) drives growth, metastasis and chemoresistance in human and canine osteosarcoma
    Pfaff, Liza E.
    Kalet, Brian T.
    Dailey, Deanna D.
    Duval, Dawn L.
    MOLECULAR CANCER RESEARCH, 2014, 12
  • [45] Posttranscriptional Destabilization of the Liver-Specific Long Noncoding RNA HULC by the IGF2 mRNA-Binding Protein 1 (IGF2BP1)
    Haemmerle, Monika
    Gutschner, Tony
    Uckelmann, Hannah
    Ozgur, Sevim
    Fiskin, Evgenij
    Gross, Matthias
    Skawran, Britta
    Geffers, Robert
    Longerich, Thomas
    Breuhahn, Kai
    Schirmacher, Peter
    Stoecklin, Georg
    Diederichs, Sven
    HEPATOLOGY, 2013, 58 (05) : 1703 - 1712
  • [46] The insulin-like growth factor (IGF) binding site of bovine insulin-like growth factor binding protein-2 (bIGFBP-2) probed by iodination
    Hobba, GD
    Forbes, BE
    Parkinson, EJ
    Francis, GL
    Wallace, JC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (48) : 30529 - 30536
  • [47] Insulin-like Growth Factor-2 (IGF-2) in Fibrosis
    Zhu, Yuhan
    Chen, Lin
    Song, Binyu
    Cui, Zhiwei
    Chen, Guo
    Yu, Zhou
    Song, Baoqiang
    BIOMOLECULES, 2022, 12 (11)
  • [48] Inhibiting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) reduces tumor development in the basal cell carcinoma mouse model PTCH plus /-
    Harris, C.
    Hajahmed, M.
    Odubanjo, O.
    Yedjou, C.
    Spiegelman, V.
    Chamcheu, J.
    Roy, T.
    Boetang, S.
    Chamcheu, R.
    Noubissi, F.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S254 - S254
  • [49] How Insulin-Like Growth Factor Hormones, IGF1 And IGF2, Engage their Cognate Receptor
    Vashisth, Harish
    Abrams, Cameron F.
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 243A - 243A
  • [50] Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability
    Zhao, Wei
    Lu, Dan
    Liu, Liang
    Cai, Juan
    Zhou, Yu
    Yang, Ying
    Zhang, Yu
    Zhang, Jun
    ONCOTARGET, 2017, 8 (55) : 93672 - 93687
12345