Acquired Robertsonian translocations in two leukemia patients

被引:7
|
作者
Chinnappan, D
Philip, A
Wu, X
Pan, A
Wyandt, HE
机构
[1] Boston Univ, Sch Med, Ctr Human Genet, Boston, MA 02118 USA
[2] Boston Univ, Sch Med, Dept Biochem, Boston, MA 02118 USA
[3] Boston Univ, Sch Med, Dept Pathol, Boston, MA 02118 USA
关键词
D O I
10.1016/S0165-4608(01)00478-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Robertsonian translocations were observed in two leukemia patients. The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute myeloid leukemia, had multiple Robertsonian translocations: der(15)t(13;15)(q11.1;p11.1), der(14;22)(q10q10), and dic(21:22)(p11.1; p11.1). Acquired multiple Robertsonian translocations have not been reported previously in leukemia. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:104 / 108
页数:5
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