Influenza vaccination in elderly people

被引：26
|
作者：
Remarque, EJ [1 ]
机构：
[1] Leiden Univ, Med Ctr, Sect Gerontol & Geriatr, NL-2300 RC Leiden, Netherlands
来源：
EXPERIMENTAL GERONTOLOGY | 1999年 / 34卷 / 03期
关键词：
influenza; aging; vaccination; antibody responses;
D O I：
10.1016/S0531-5565(99)00007-8
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Influenza is an important cause of morbidity and mortality in the elderly. Influenza vaccine has been shown to successfully reduce influenza- and pneumonia-associated hospitalizations and deaths, but the antibody induction by influenza vaccines is not always optimal in the elderly. The lower serological efficacy of influenza vaccines that is often observed in the elderly may be due to a multitude of factors. Here we will discuss some of these factors. These include health status and previous exposures to influenza viruses. In addition, we will discuss possibilities to improve antibody responses to influenza vaccination. (C) 1999 Elsevier Science Inc. All rights reserved.
引用
收藏
页码：445 / 452
页数：8
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