Rhodium-catalyzed intramolecular [4+2] cycloadditions of alkynyl halides

被引：43
|
作者：
Yoo, WJ [1 ]
Allen, A [1 ]
Villeneuve, K [1 ]
Tam, W [1 ]
机构：
[1] Univ Guelph, Guelph Waterloo Ctr Grad Work Chem & Biochem, Dept Chem, Guelph, ON N1G 2W1, Canada
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 26期
关键词：
D O I：
10.1021/ol052412o
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Cationic rhodium(l)-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were found to occur in good yields (70-87%). The halide moiety is compatible with the cycloaddition reactions, and no oxidative insertion to the alkynyl halide was observed. The halogen-containing cycloadducts could be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.
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收藏
页码：5853 / 5856
页数：4
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