Targeting Notch and Hedgehog Embryonic Signaling Pathways Has Potent Anti-Tumor Activity in Myeloma and Is Effective in Myeloma Bone Disease.

被引：0

作者：

Schwarzer, Rolf ^{[1
]}

Schuenemann, Nicole ^{[1
]}

Wong, David M. ^{[2
]}

Bogen, Bjarne ^{[3
,4
]}

Bommert, Kurt ^{[5
]}

Doerken, Bernd ^{[1
]}

Manz, Rudolf ^{[2
]}

Jundt, Franziska ^{[1
]}

机构：

[1] Univ Med Berlin, Charite, Dept Hematol & Oncol, Berlin, Germany

[2] Med Univ Lubeck, Inst Syst Inflammat Res, D-23538 Lubeck, Germany

[3] Univ Oslo, Dept Immunol & Transfus Med, Ctr Immune Regulat, Oslo, Norway

[4] Oslo Univ Hosp, Oslo, Norway

[5] Univ Wurzburg, Med Ctr, D-97070 Wurzburg, Germany

来源：

BLOOD | 2012年 / 120卷 / 21期

关键词：

D O I：

10.1182/blood.V120.21.2938.2938

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2938

引用

页数：2

共 46 条

[1] Targeting Wnt signaling in myeloma in vivo;: Differential effects on tumor burden and myeloma bone disease
Edwards, Claire M.
Edwards, James R.
Lwin, Seint T.
Mundy, Gregory R.
[J]. BLOOD, 2007, 110 (11) : 249A - 249A
[2] Targeting EZH2 in Multiple Myeloma-Multifaceted Anti-Tumor Activity
Alzrigat, Mohammad
Jernberg-Wiklund, Helena
Licht, Jonathan D.
[J]. EPIGENOMES, 2018, 2 (03)
[3] Biological pathways and in vivo anti-tumor activity induced by atiprimod in multiple myeloma (MM).
Neri, Paola
Tassone, Pierfrancesco
Shammas, Masood
Yasui, Hiroshi
Schipani, Ernestina
Batchu, Ramesh B.
Blotta, Simona
Prabhala, Rao
Catley, Laurence
Hamasaki, Makoto
Hideshima, Teru
Chauhan, Dharminder
Jacob, Gary S.
Picker, Donald
Venuta, Salvatore
Anderson, Kenneth C.
Munshi, Nilchil C.
[J]. BLOOD, 2006, 108 (11) : 986A - 986A
[4] Synergistic Anti-Tumor Activity by Targeting Multiple Signaling Pathways in Ovarian Cancer
Wen, Wei
Han, Ernest S.
Dellinger, Thanh H.
Lu, Leander X.
Wu, Jun
Jove, Richard
Yim, John H.
[J]. CANCERS, 2020, 12 (09) : 1 - 17
[5] Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma
Oden, Felix
Marino, Stephen F.
Brand, Janko
Scheu, Susanne
Kriegel, Cathleen
Olal, Daniel
Takvorian, Anna
Westermann, Joerg
Yilmaz, Buket
Hinz, Michael
Daumke, Oliver
Hoepken, Uta E.
Mueller, Gerd
Lipp, Martin
[J]. MOLECULAR ONCOLOGY, 2015, 9 (07) : 1348 - 1358
[6] Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma
Jakubikova, Jana
Cervi, David
Ooi, Melissa
Kim, Kihyun
Nahar, Sabikun
Klippel, Steffen
Cholujova, Dana
Leiba, Merav
Daley, John F.
Delmore, Jake
Negri, Joseph
Blotta, Simona
McMillin, Douglas W.
Hideshima, Teru
Richardson, Paul G.
Sedlak, Jan
Anderson, Kenneth C.
Mitsiades, Constantine S.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2011, 96 (08): : 1170 - 1179
[7] A Novel Agent Tasquinimod Demonstrates a Potent Anti-Tumor Activity in Pre-Clinical Models of Multiple Myeloma
Ramachandran, Indu R.
Lin, Cindy
Chase, Tess
Gabrilovich, Dmitry
Nefedova, Yulia
[J]. BLOOD, 2014, 124 (21)
[8] Selective Activation of the Non-Classical Estrogen Receptor Gper Elicits Potent Anti-Tumor Activity in Multiple Myeloma
Amodio, Nicola
Romeo, Enrica
Stamato, Maria Angelica
Morelli, Eugenio
Fulciniti, Mariateresa
Raimondi, Lavinia
Leotta, Marzia
Di Martino, Maria Teresa
Tagliaferri, Pierosandro
Munshi, Nikhil C.
Tassone, Pierfrancesco
[J]. BLOOD, 2015, 126 (23)
[9] Synergistic Anti-Tumor Effects in RAS Mut Multiple Myeloma By Targeting MAP4K2 and RAS Pathways
Fu, Jing
Li, Shirong
Liu, Guifen
Ma, Huihui
Marcireau, Christophe
Mapara, Markus
Lentzsch, Suzanne
[J]. BLOOD, 2023, 142
[10] Nifuroxazide inhibits STAT3 function. and shows potent anti-tumor activity against multiple myeloma.
Nelson, Erik A.
Hideshima, Teru
Gashin, Laurie
Walker, Sarah R.
Lynch, Rebecca A.
Chauhan, Dharminder
Anderson, Kenneth C.
Frank, David A.
[J]. BLOOD, 2006, 108 (11) : 985A - 985A

← 1 2 3 4 5 →