One-pot reductive amination of aldehydes by the dihydropyridine in water

被引：5
|
作者：
Ghafuri, H. [1 ]
Hashemi, M. M. [2 ]
机构：
[1] Iran Univ Sci & Technol, Dept Chem, Tehran, Iran
[2] Sharif Univ Technol, Dept Chem, Tehran, Iran
来源：
SCIENTIA IRANICA | 2012年 / 19卷 / 06期
关键词：
Aldehydes; Dihydropyridine; Reductive amination; Secondary amines; Water chemistry; KETONES; BOROHYDRIDE; AMINE;
D O I：
10.1016/j.scient.2012.10.030
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
An efficient, highly chemoselective and simple synthesis of secondary amines via reductive amination of aldehydes, aromatic amines and inexpensive and easily accessible Diethyl 2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (DHP) in the presence of catalytic amounts of p-toluenesulfonic acid (PTSA) in water in good to excellent yields is reported. (C) 2012 Sharif University of Technology. Production and hosting by Elsevier B.V. All rights reserved.
引用
收藏
页码：1591 / 1593
页数：3
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