Discrete modeling of aggressive tumor growth with gradual effect of chemotherapy

被引：5

作者：

Solis, Francisco J. ^{[1
]}

Delgadillo, Sandra E. ^{[2
]}

机构：

[1] CIMAT, Guanajuato Mexico 36000, Mexico

[2] Univ Autonoma Aguascalientes, Aguascalientes Mexico 20100, Mexico

来源：

MATHEMATICAL AND COMPUTER MODELLING | 2013年 / 57卷 / 7-8期

关键词：

Heterogeneous tumors; Competence; Chemotherapy; CANCER-CHEMOTHERAPY; MATHEMATICAL-MODEL; DRUG-RESISTANCE; HETEROGENEOUS TUMORS; CELL-POPULATIONS;

D O I：

10.1016/j.mcm.2011.12.032

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Discrete mathematical models are proposed to study the dynamics of interacting cells of an organism that is affected by an aggressive heterogeneous tumor. The models include the application of a chemotherapy treatment with a gradual effect. Another factor included in the models is the competence among the different tumor cells. An effective treatment index is introduced in order to analyze the evolution of the tumor and to compare different treatments. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1919 / 1926

页数：8

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