Index of myocardial injury CIIS and mortality of patients with chronic obstructive pulmonary disease

Aim of the study was to assess informative power of the Cardiac Infarction Injury Score (CIIS) in patients with chronic obstructive pulmonary disease (COPD) to determine the role of CIIS in prognosis of death of patients with COPD. We examined 124 patients with COPD and followed 76 of them for 4 years. During follow up 16 patients (21.1%) died. Patient, who died 3.1 times more often had myocardial infarctions (P < 0.05), 3,7 times more often - signs of heart failure (p < 0.001), 2 times more often - rhythm disturbances. In patients with severe and very severe course of COPD CIIS > 20 was detected 1.8 times more often than in patients with moderately severe disease. Difference in CIIS between survivors and those who died was significant (p < 0.001). It was demonstrated that CIIS can be used for stratification of risk of death in patients with COPD. CIIS above 20 is defined as prognostically unfavorable factor or as risk factor of death in patients whith COPD while CIIS < 10 is associated with lower probability of unfavorable outcome.