Transplantation for Alcohol-related Liver Disease: Is It Fair?

被引:18
|
作者
Mellinger, Jessica L. [1 ]
Volk, Michael L. [2 ,3 ]
机构
[1] Univ Michigan Hosp, Div Gastroenterol, Taubman Ctr 3912, 1500 Med Ctr Dr,SPC 5362, Ann Arbor, MI 48109 USA
[2] Loma Linda Univ Hlth, Loma Linda Univ Med, Div Gastroenterol, 25865 Barton Rd,Suite 101, Loma Linda, CA 92354 USA
[3] Loma Linda Univ Hlth, Loma Linda Univ Med, Inst Transplantat, 25865 Barton Rd,Suite 101, Loma Linda, CA 92354 USA
来源
ALCOHOL AND ALCOHOLISM | 2018年 / 53卷 / 02期
关键词
HEPATITIS; ALLOCATION; RELAPSE; RESPONSIBILITY; METAANALYSIS; SELECTION; CIRRHOSIS; PRIORITY;
D O I
10.1093/alcalc/agx105
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Aims: Alcohol-related liver disease (ALD) is the second leading cause of liver transplantation performed in the USA and Europe. We aimed to provide a narrative review of the major ethical issues governing transplantation for ALD. Methods: We performed a narrative review of the ethical concepts in organ allocation for ALD, including alcoholic hepatitis. Results: Ethical concerns regarding organ allocation for ALD involve issues of urgency, utility and justice. Post-transplant outcomes for ALD patients are good and ethical considerations limiting organs solely because of alcohol etiology do not bear scrutiny. Conclusion: ALD will continue to be a major cause for liver failure. The main criteria for transplant in ALD should be the patient's risk of return to harmful drinking, alongside standard assessments of physical and psychosocial fitness for transplant.
引用
收藏
页码:173 / 177
页数:5
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