WNT signaling and lymphocyte development

被引：108

作者：

van de Wetering, M ^{[1
]}

de Lau, W ^{[1
]}

Clevers, H ^{[1
]}

机构：

[1] UMC Utrecht, Dept Immunol, NL-3584 CX Utrecht, Netherlands

来源：

CELL | 2002年 / 109卷

关键词：

D O I：

10.1016/S0092-8674(02)00709-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.

引用

页码：S13 / S19

页数：7

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