Therapeutic hypothermia after out-of-hospital cardiac arrest due to Brugada syndrome

被引：12

作者：

Kurisu, Satoshi ^{[1
]}

Inoue, Ichiro ^{[1
]}

Kawagoe, Takuji ^{[1
]}

Ishihara, Masaharu ^{[1
]}

Shimatani, Yuji ^{[1
]}

Nakama, Yasuharu ^{[1
]}

Maruhashi, Tatsuya ^{[1
]}

Kagawa, Eisuke ^{[1
]}

Dai, Kazuoki ^{[1
]}

Aokage, Toshiyuki ^{[1
]}

Matsushita, Junichi ^{[1
]}

Ikenaga, Hiroki ^{[1
]}

机构：

[1] Hiroshima City Hosp, Dept Cardiol, Naka Ku, Hiroshima 7308518, Japan

来源：

RESUSCITATION | 2008年 / 79卷 / 02期

关键词：

Cardiac arrest; Hypothermia; Electrocardiography;

D O I：

10.1016/j.resuscitation.2008.05.007

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 56-year-old man was admitted to our hospital after successful resuscitation for out-of-hospital cardiac arrest. Electrocardiogram on admission showed right bundle branch block and ST segment elevation in leads V1-3. Subsequent intravenous infusion of isoproterenol rapidly resolved ST segment elevation, suggesting Brugada syndrome. Therapeutic hypothermia, that was performed with a target temperature of 34.0 degrees C did not induce ST segment elevation in leads V1-3. The J-ST segment elevation rather became much more normal, suggesting a beneficial effect of mild therapeutic hypothermia. Serial. ECG showed the temporal variation of ST segment elevation, and pilsicainide challenge test showed the occurrence of ST segment elevation, confirming the diagnosis of Brugada syndrome. Clinical observation suggested that mild therapeutic hypothermia reversed the Brugada phenotype through the prevention of fever as well as being indicated for cerebral protection after cardiac arrest. In conclusion, therapeutic hypothermia with a temperature of 34.0 degrees C can be used safety in Brugada syndrome. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

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页码：332 / 335

页数：4

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