Magnetic resonance spectroscopy (NMR and electron spin resonance [ESR]) yields uniquely both dynamic and structural information on lipids and proteins in biological and bilayer membranes. Recent advances have been made in elucidating the three-dimensional structure of membrane-embedded proteins by solid state NMR techniques and by site-directed ESR spin labelling. (C) Current Chemistry Ltd.
机构:
Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAScripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA
Eddy, Matthew T.
Yu, Tsyr-Yan
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Acad Sinica, Inst Atom & Mol Sci, Taipei 10617, TaiwanScripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA