Modular organization of the mammalian Golgi apparatus

被引：53
|
作者：
Nakamura, Nobuhiro [1 ]
Wei, Jen-Hsuan [2 ]
Seemann, Joachim [2 ]
机构：
[1] Kyoto Sangyo Univ, Dept Mol Biosci, Fac Life Sci, Kita Ku, Kyoto 6038555, Japan
[2] Univ Texas SW Med Ctr Dallas, Dept Cell Biol, Dallas, TX 75390 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 2012年 / 24卷 / 04期
关键词：
REGULATES GOLGI; MATRIX PROTEIN; BREFELDIN-A; UNCONVENTIONAL SECRETION; CELL-MIGRATION; MITOTIC GOLGI; GRASP PROTEIN; COMPLEX; MEMBRANE; ER;
D O I：
10.1016/j.ceb.2012.05.009
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The Golgi apparatus is essential for post-translational modifications and sorting of proteins in the secretory pathway. In addition, it further performs a broad range of specialized functions. This functional diversity is achieved by combining basic morphological modules of cisternae into higher ordered structures. Linking cisternae into stacks that are further connected through tubules into a continuous Golgi ribbon greatly increases its efficiency and expands its repertoire of functions. During cell division, the different modules of the Golgi are inherited by different mechanisms to maintain its functional and morphological composition.
引用
收藏
页码：467 / 474
页数：8
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