An unusual human papillomavirus type 82 detection in laryngeal squamous cell carcinoma: Case report and review of literature

被引:8
|
作者
Si-Mohamed, Ali [1 ]
Badoual, Cecile [2 ]
Hans, Stephane [3 ]
Pere, Helene [1 ]
Tartour, Eric [4 ]
Brasnu, Daniel [3 ]
机构
[1] Univ Paris Descartes Sorbonne Paris Cite, HEGP, AP HP, Virol Lab, F-75908 Paris 15, France
[2] Univ Paris Descartes Sorbonne Paris Cite, HEGP, AP HP, Serv Anat Pathol, F-75908 Paris 15, France
[3] Univ Paris Descartes Sorbonne Paris Cite, HEGP, AP HP, Serv Otorhinolaryngol & Chirurg Cervicofaciale, F-75908 Paris 15, France
[4] Univ Paris Descartes Sorbonne Paris Cite, HEGP, AP HP, Immunol Lab, F-75908 Paris 15, France
关键词
HPV-82; Squamous cell carcinoma of larynx; p16; immunochemistry; Dysphonia; Vocal cord; INVASIVE CERVICAL-CANCER; NECK-CANCER; POOLED ANALYSIS; HEAD; DNA; PREVALENCE; WORLDWIDE; CHILDREN; YOUNGER; METAANALYSIS;
D O I
10.1016/j.jcv.2012.02.024
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Squamous cell carcinoma (SCC) of the larynx is extremely rare in adolescent or younger adult and typically has an aggressive nature. The mechanism of laryngeal oncogenesis is complex and little is known about the role of human papillomaviruses (HPVs) in SCC in young age. HPV infection may occur during birth or latter by oro-genital contact. Most HPV genotypes detected were HPV 6, 11, 16, 18, 33 and 51. Herein, we report a case of invasive laryngeal SCC expressing an HPV 82 in an 18 year-old man with a history of unexplored severe acute dysphonia that started in early childhood. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:190 / 193
页数:4
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