CAR T cells in marginal zone lymphoma (MZL) models with acquired resistance to PI3K and BTK inhibitors

被引：0
|
作者：
Wang, S. [1 ,2 ]
Arribas, A. J. [3 ]
Tarantelli, C. [3 ]
Pradier, A. [1 ,2 ]
Zucca, E. [3 ]
Rossi, D. [3 ]
Simonetta, F. [1 ,2 ]
Bertoni, F. [3 ]
机构：
[1] Univ Geneva, Geneva Univ Hosp, Dept Oncol, Div Hematol, Geneva, Switzerland
[2] Translat Res Ctr Oncohaematol, Geneva, Switzerland
[3] USI, Fac Biomed Sci, Inst Oncol Res, Bellinzona, Switzerland
来源：
EUROPEAN JOURNAL OF CANCER | 2022年 / 174卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
297
引用
收藏
页码：S106 / S106
页数：1
相关论文
共 50 条
  • [41] ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms
    Arribas, Alberto J.
    Napoli, Sara
    Cascione, Luciano
    Barnabei, Laura
    Sartori, Giulio
    Cannas, Eleonora
    Gaudio, Eugenio
    Tarantelli, Chiara
    Mensah, Afua A.
    Spriano, Filippo
    Zucchetto, Antonella
    Rossi, Francesca M.
    Rinaldi, Andrea
    Castro de Moura, Manuel
    Jovic, Sandra
    Bordone Pittau, Roberta
    Stathis, Anastasios
    Stussi, Georg
    Gattei, Valter
    Brown, Jennifer R.
    Esteller, Manel
    Zucca, Emanuele
    Rossi, Davide
    Bertoni, Francesco
    MOLECULAR CANCER THERAPEUTICS, 2024, 23 (03) : 368 - 380
  • [42] Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations
    Bonelli, M.
    Cavazzoni, A.
    La Monica, S.
    Galetti, M.
    Caffarra, C.
    Cretella, D.
    Saccani, F.
    Fumarola, C.
    Alfieri, R.
    Petronini, P. G.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S166 - S167
  • [43] Selective PI3K and dual PI3K/mTOR inhibitors enhance the efficacy of endocrine therapies in breast cancer models
    Friedman, L.
    Ross, L. B.
    Wallin, J.
    Guan, J.
    Prior, W. W.
    Wu, E.
    Nannini, M.
    Sampath, D.
    CANCER RESEARCH, 2012, 72
  • [44] Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells
    Ramdas, Baskar
    Yuen, Lisa Deng
    Palam, Lakshmi Reddy
    Patel, Roshini
    Pasupuleti, Santhosh Kumar
    Jideonwo, Victoria
    Zhang, Ji
    Maguire, Callista
    Wong, Eric
    Kanumuri, Rahul
    Zhang, Chujing
    Sandusky, George
    Chan, Rebecca J.
    Zhang, Chi
    Stieglitz, Elliot
    Haneline, Laura
    Kapur, Reuben
    MOLECULAR THERAPY, 2022, 30 (07) : 2505 - 2521
  • [45] Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors
    Qian, Xiao-jun
    Li, Yun-tian
    Yu, Yan
    Yang, Fen
    Deng, Rong
    Ji, Jiao
    Jiao, Lin
    Li, Xuan
    Wu, Rui-Yan
    Chen, Wen-Dan
    Feng, Gong-Kan
    Zhu, Xiao-Feng
    ONCOTARGET, 2015, 6 (07) : 5134 - 5146
  • [46] Strategies for Overcoming Inherent and Acquired Resistance to EGFR Inhibitors by Targeting Downstream Effectors in the RAS/PI3K Pathway
    Weickhardt, A. J.
    Tebbutt, N. C.
    Mariadason, J. M.
    CURRENT CANCER DRUG TARGETS, 2010, 10 (08) : 824 - 833
  • [47] The BTK/PI3K/BRD4 axis inhibitor SRX3262 overcomes Ibrutinib resistance in mantle cell lymphoma
    Pal, Dhananjaya
    Vann, Kendra R.
    Joshi, Shweta
    Sahar, Namood E.
    Morales, Guillermo A.
    El-Gamal, Dalia
    Kutateladze, Tatiana G.
    Durden, Donald L.
    ISCIENCE, 2021, 24 (09)
  • [48] Activation of PI3K/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells
    Chen, Kuen-Feng
    Feng, Wen-Chi
    Hsu, Chih-Hung
    Chen, Pei-Jer
    Cheng, Ann-Lii
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [49] Effects of PI3K inhibitors on endocrine-resistant cell lines and differences in the characteristics of ER positive breast cancer cells after acquired resistance to the inhibitors
    Tokuda, Emi
    Komatsu, Takayuki
    Sasaki, Shunta
    Tsuboi, Kouki
    Nakamura, Misato
    Iida, Masafumi
    Niwa, Toshifumi
    Saito, Mitsue
    Hayashi, Shin-Ichi
    CANCER RESEARCH, 2018, 78 (04)
  • [50] Impact of PI3K/mTOR inhibitors on the development of taxane resistance.
    Esplund, Jayda Nicole
    Xu, Bing
    Elsey, Rachel J.
    Messner, Tobias
    Williams, Casey B.
    CANCER RESEARCH, 2021, 81 (13)
12345