Synthesis of 3,5-disubstituted isoxazolines as potential antibacterial and antifungal agents

被引：0
|
作者：
Imran, M [1 ]
Khan, SA [1 ]
机构：
[1] Hamdard Univ, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2004年 / 13卷 / 03期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of 3,5-disubstituted isoxazolines were prepared by the condensation of hydroxylamine hydrochloride with various chalcones. The structures of new compounds were established on the basis of IR and H-1 NMR spectral data and their antibacterial and antifungal activities were investigated. The compounds showed significant antifungal activity against Candida albicans and moderate to feeble antibacterial activity against E. coli and S. aureus.
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页码：213 / 216
页数：4
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