Synthesis and biological evaluation of selective ErbB2 (Her2) inhibitors for the treatment of cancer

被引:0
|
作者
Kauffman, Goss S. [1 ]
Lippa, Blaise [1 ]
Arcari, Joel [1 ]
Kwan, Tricia A. [1 ]
Bhattacharya, Samit K. [1 ]
Pustilnik, Leslie R. [1 ]
Su, Chunyan [1 ]
Moyer, James D. [1 ]
Ma, Ling [1 ]
Campbell, Mary [1 ]
Steyn, Stefan [1 ]
机构
[1] Pfizer Global Res & Dev, Dept Canc Res, Groton, CT 06340 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
245-MEDI
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Essential roles of Her2/erbB2 in cardiac development and function
    Negro, A
    Brar, BK
    Lee, KF
    RECENT PROGRESS IN HORMONE RESEARCH, VOL 59: CARDIOVASCULAR ENDOCRINOLOGY & OBESITY, 2004, 59 : 1 - 12
  • [32] Single Domain Monoclonal Antibody Specific for Her2 or ERBB2
    Omidfar, Kobra
    HYBRIDOMA, 2011, 30 (01): : 105 - 105
  • [33] ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia
    Sunil K. Joshi
    Jamie M. Keck
    Christopher A. Eide
    Daniel Bottomly
    Elie Traer
    Jeffrey W. Tyner
    Shannon K. McWeeney
    Cristina E. Tognon
    Brian J. Druker
    Leukemia, 2020, 34 : 2798 - 2804
  • [34] HER2 therapy - HER2 (ERBB2): functional diversity from structurally conserved building blocks
    Landgraf, Ralf
    BREAST CANCER RESEARCH, 2007, 9 (01)
  • [35] Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu)
    Reid, Alison
    Vidal, Laura
    Shaw, Heather
    de Bono, Johann
    EUROPEAN JOURNAL OF CANCER, 2007, 43 (03) : 481 - 489
  • [36] Amplification of ERBB2 (HER2) in embryonal rhabdomyosarcoma: A potential treatment target in rare cases?
    Mitra, Shamik
    Sydow, Saskia
    Magnusson, Linda
    Piccinelli, Paul
    Tornudd, Lisa
    Ora, Ingrid
    Ljungman, Gustaf
    Sandgren, Johanna
    Gisselsson, David
    Mertens, Fredrik
    GENES CHROMOSOMES & CANCER, 2022, 61 (01): : 5 - 9
  • [37] The HER2/neu (erbB2) polymorphism, body mass index, and the risk of endometrial cancer
    Lee, J.
    Tong, S.
    Lee, K.
    Kim, J.
    Kwon, Y.
    Kim, J.
    Kim, Y.
    Yei, J.
    Do, Y.
    Kwon, S.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [38] Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells
    Marcus, Elizabeth A.
    Tokhtaeva, Elmira
    Turdikulova, Shahlo
    Capri, Joseph
    Whitelegge, Julian P.
    Scott, David R.
    Sachs, George
    Berditchevski, Fedor
    Vagin, Olga
    BIOCHEMICAL JOURNAL, 2016, 473 : 1703 - 1718
  • [39] Design, Synthesis and Biological Evaluation of Lapatinib Derivatives as HER1/HER2 Inhibitors
    Lyu, Aifeng
    Fang, Lei
    Gou, Shaohua
    Liu, Xia
    LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 12 (07) : 574 - 584
  • [40] Targeting HER2 in Colorectal Cancer: The Landscape of Amplification and Short Variant Mutations in ERBB2 and ERBB3
    Ross, Jeffrey S.
    Fakih, Marwan
    Ali, Siraj M.
    Elvin, Julia A.
    Schrock, Alexa B.
    Suh, James
    Vergilio, Jo-Anne
    Ramkissoon, Shakti
    Severson, Eric
    Daniel, Sugganth
    Fabrizio, David
    Frampton, Garrett
    Sun, James
    Miller, Vincent A.
    Stephens, Philip J.
    Gay, Laurie M.
    CANCER, 2018, 124 (07) : 1358 - 1373