Objective To evaluate the impact of increased experience in robot-assisted partial nephrectomy (RAPN) on perioperative and oncological outcomes To detail the complications encountered in establishing a RAPN programme at a tertiary referral centre and the factors associated with these complications Patients and Methods The initial consecutive 233 patients undergoing RAPN between March 2008 and May 2012 at our institution were identified. Patients were divided into quartiles to evaluate outcomes, and uni- and multivariate predictors of complications were calculated Results In progressive quartiles, patients tended to have more complex renal tumours as evaluated by R.E.N.A.L. nephrometry (P<0.01) or preoperative aspects and dimensions used for an anatomical classification (PADUA) scores (P=0.003), and percentage endophytic (P=0.01). Developing technique increased the patients undergoing unclamped PN (P<0.01). The mean time in the operating room (from skin incision to closure) decreased significantly from 225 to 183min (P<0.01) and warm ischaemia time decreased from 28 to 15min, when clamping (P<0.01). Clavien graded complication rate (P=0.26) and positive margin rate (P=0.32) was unchanged by quartile. Conclusion We show that increasing experience allows more complex tumours to be removed with similar outcomes in patients undergoing RAPN. The complication rates and perioperative outcomes were similar in four successive quartiles of an initial experience of RAPN.
机构:
Northeast Ohio Med Univ, Akron Gen Med Ctr, Dept Urol, Akron, OH 44305 USANortheast Ohio Med Univ, Akron Gen Med Ctr, Dept Urol, Akron, OH 44305 USA
Pahouja, Gaurav
Patel, Kalpit
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Northeast Ohio Med Univ, Akron Gen Med Ctr, Dept Urol, Akron, OH 44305 USANortheast Ohio Med Univ, Akron Gen Med Ctr, Dept Urol, Akron, OH 44305 USA
Patel, Kalpit
Ricchiuti, Daniel J.
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St Elizabeth Hlth Ctr, Div Urol, Youngstown, OH USANortheast Ohio Med Univ, Akron Gen Med Ctr, Dept Urol, Akron, OH 44305 USA
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Osped San Raffaele, Dept Urol, Milan, ItalyPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Capitanio, Umberto
Ahlawat, Rajesh
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Medanta Medic Hosp, Dept Urol, New Delhi, IndiaPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Ahlawat, Rajesh
Rawal, Sudhir
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Rajiv Gandhi Canc Inst & Res Ctr, Dept Urol, New Delhi, IndiaPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Rawal, Sudhir
Buffi, Nicolo M.
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Humanitas Res Hosp, Dept Urol, Milan, ItalyPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Buffi, Nicolo M.
Sivaraman, Ananthakrishnan
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Apollo Hosp, Dept Urol, Chennai, Tamil Nadu, IndiaPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Sivaraman, Ananthakrishnan
Maes, Kris K.
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Hosp Da Luz, Ctr Robot & Minimally Invas Surg, Dept Urol, Luz Saude, PortugalPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Maes, Kris K.
Gautham, Gagan
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Max Hosp, Max Inst Canc Care, Dept Urol, New Delhi, IndiaPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
Gautham, Gagan
Porpiglia, Francesco
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San Luigi Gonzaga Hosp Orbassano, Dept Urol, Turin, ItalyPeter MacCallum Canc Ctr, Div Canc Surg, Genitourinary Oncol, 305 Grattan St, Melbourne, Vic 3000, Australia
机构:
Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Hu, Jim C.
Treat, Eric
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Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Treat, Eric
Filson, Christopher P.
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Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Filson, Christopher P.
McLaren, Ian
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Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
McLaren, Ian
Xiong, Siwei
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Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Xiong, Siwei
Stepanian, Sevan
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Swedish Med Ctr, Seattle, WA USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Stepanian, Sevan
Hafez, Khaled S.
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Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Hafez, Khaled S.
Weizer, Alon Z.
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Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
Weizer, Alon Z.
Porter, James
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Swedish Med Ctr, Seattle, WA USAUniv Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA