A THERAPY INACTIVATING THE TUMOR ANGIOGENIC FACTORS

被引：2

作者：

Morales-Rodrigo, Cristian ^{[1
]}

机构：

[1] Univ Seville, Fac Matemat, Dept Ecuac Diferenciales & Anal Numer, E-41012 Seville, Spain

来源：

MATHEMATICAL BIOSCIENCES AND ENGINEERING | 2013年 / 10卷 / 01期

关键词：

Chemotaxis; anti-angiogenic therapy; ELLIPTIC PROBLEMS; MODEL; BOUNDARY;

D O I：

10.3934/mbe.2013.10.185

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This paper is devoted to a nonlinear system of partial differential equations modeling the effect of an anti-angiogenic therapy based on an agent that binds to the tumor angiogenic factors. The main feature of the model under consideration is a nonlinear flux production of tumor angiogenic factors at the boundary of the tumor. It is proved the global existence for the nonlinear system and the effect in the large time behavior of the system for high doses of the therapeutic agent.

引用

页码：185 / 198

页数：14

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