Isolation and Characterization of Low-Molecular-Weight Chromium-binding Substance (LMWCr) from Chicken Liver

被引：8
|
作者：
Viera, Margarita [1 ]
Davis-McGibony, C. Michele [1 ]
机构：
[1] Georgia So Univ, Dept Chem, Statesboro, GA 30460 USA
来源：
PROTEIN JOURNAL | 2008年 / 27卷 / 06期
关键词：
Chromium; Chicken; Low-molecular-weight chromium-binding substance; Chromodulin;
D O I：
10.1007/s10930-008-9146-z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chromodulin (also known as low-molecular-weight chromium-binding substance, LMWCr) is a chromium-binding oligopeptide proposed to play a role in insulin signaling and chromium transport in mammals. This laboratory has isolated and purified this material from a non-mammalian source, an avian. Spectroscopic and physical characterization of the isolated material suggests the material is an oligopeptide with a multinuclear chromium assembly bridged via asparatate and glutamate residues very similar to its mammalian counterparts. The isolated material also possesses a biological activity similar to other LMWCr isolates.
引用
收藏
页码：371 / 375
页数：5
相关论文
共 50 条
  • [1] Isolation and Characterization of Low-Molecular-Weight Chromium-binding Substance (LMWCr) from Chicken Liver
    Margarita Viera
    C. Michele Davis-McGibony
    [J]. The Protein Journal, 2008, 27 : 371 - 375
  • [2] The binding of trivalent chromium to low-molecular-weight chromium-binding substance (LMWCr) and the transfer of chromium from transferrin and chromium picolinate to LMWCr
    Sun, YJ
    Ramirez, J
    Woski, SA
    Vincent, JB
    [J]. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2000, 5 (01): : 129 - 136
  • [3] The binding of trivalent chromium to low-molecular-weight chromium-binding substance (LMWCr) and the transfer of chromium from transferrin and chromium picolinate to LMWCr
    Y. Sun
    J. Ramirez
    S. A. Woski
    J. B. Vincent
    [J]. JBIC Journal of Biological Inorganic Chemistry, 2000, 5 : 129 - 136
  • [4] Low-molecular-weight chromium-binding substance from chicken liver and American alligator liver
    Hatfield, M. Jason
    Gillespie, Shanna
    Chen, Yuan
    Li, Zhong
    Cassady, Carolyn J.
    Vincent, John B.
    [J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2006, 144 (04): : 423 - 431
  • [5] Low-molecular-weight chromium-binding substance (LMWCr) may bind and carry Cr(III) from the endosome
    Edwards, Kyle C.
    Gannon, Michael W.
    Frantom, Patrick A.
    Vincent, John B.
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 2021, 223
  • [6] A LOW-MOLECULAR-WEIGHT, CHROMIUM-BINDING SUBSTANCE IN MAMMALS
    YAMAMOTO, A
    WADA, O
    ONO, T
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1981, 59 (03) : 515 - 523
  • [7] DISTRIBUTION AND CHROMIUM-BINDING CAPACITY OF A LOW-MOLECULAR-WEIGHT, CHROMIUM-BINDING SUBSTANCE IN MICE
    YAMAMOTO, A
    WADA, O
    ONO, T
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 1984, 22 (02) : 91 - 102
  • [8] Characterization of the Organic Component of Low-Molecular-Weight Chromium-Binding Substance and Its Binding of Chromium
    Chen, Yuan
    Watson, Heather M.
    Gao, Junjie
    Sinha, Sarmistha Halder
    Cassady, Carolyn J.
    Vincent, John B.
    [J]. JOURNAL OF NUTRITION, 2011, 141 (07): : 1225 - 1232
  • [9] Mechanism of chromium action: low-molecular-weight chromium-binding substance
    Vincent, JB
    [J]. JOURNAL OF INORGANIC BIOCHEMISTRY, 1999, 74 (1-4) : 329 - 329
  • [10] CHARACTERIZATION OF LOW-MOLECULAR-WEIGHT CHROMIUM-BINDING PROTEIN FROM BOVINE LIVER
    DAVIS, CM
    VINCENT, JB
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 406 - INOR
12345