Copper-free 'click': 1,3-dipolar cycloaddition of azides and arynes

被引：93
|
作者：
Campbell-Verduyn, Lachlan [1 ]
Elsinga, Philip H. [2 ]
Mirfeizi, Leila [2 ]
Dierckx, Rudi A. [2 ]
Feringa, Ben L. [1 ]
机构：
[1] Univ Groningen, Stratingh Inst Chem, Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2008年 / 6卷 / 19期
关键词：
D O I：
10.1039/b812403e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Arynes formed through fluoride-promoted ortho-elimination of o-(trimethylsilyl)aryl triflates can undergo [3 + 2] cycloaddition with various azides to form substituted benzotriazoles. The rapid reaction times and mild conditions make this an attractive variation of the classical 'click' reaction of azides and alkynes.
引用
收藏
页码：3461 / 3463
页数：3
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