New 19-Oxygenated Steroids from the Soft Coral Nephthea chabrolii

被引:11
|
作者
Wang, Shang-Kwei [1 ,2 ]
Puu, Shyh-Yueh [3 ]
Duh, Chang-Yih [1 ,3 ]
机构
[1] Natl Sun Yat Sen Univ, Asia Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan
[2] Kaohsiung Med Univ, Dept Microbiol, Kaohsiung 807, Taiwan
[3] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 804, Taiwan
来源
MARINE DRUGS | 2012年 / 10卷 / 06期
关键词
Nephthea chabrolii; 19-oxygenated steroids; cytotoxicity; anti-HCMV; PRENYLBICYCLOGERMACRANE DITERPENOIDS; ERECTA; BRASSICA; SESQUITERPENOIDS; METABOLITES; ELONGATA;
D O I
10.3390/md10061288
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
In order to search for novel bioactive substances from marine organisms, we investigated the acetone extract of the soft coral Nephthea chabrolii collected at San-Hsian-Tai, Taitong County, Taiwan. From this extract three new 19-oxygenated steroids, nebrosteroids N-P (1-3) were isolated. The structures of these compounds were elucidated by extensive spectroscopic analyses.
引用
收藏
页码:1288 / 1296
页数:9
相关论文
共 50 条
  • [41] NEW SESQUITERPENOIDS AND DITERPENOIDS FROM THE SOFT CORAL NEPHTHEA-CHABROLI OF INDIAN COAST
    ANJANEYULU, ASR
    PRAKASH, CVS
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1995, 34 (01): : 32 - 39
  • [42] Two new 19-oxygenated ent-kaurane diterpenoids from lsodon pharicus
    Yong Zhao~(a
    ChineseChemicalLetters, 2010, 21 (01) : 81 - 84
  • [43] New 19-oxygenated steroid from the South China Sea gorgonian Dichotella gemmacea
    Cao, Fei
    Liu, Hai-Yan
    Zhao, Jie
    Fang, Yu-Chun
    Wang, Chang-Yun
    NATURAL PRODUCT RESEARCH, 2015, 29 (02) : 169 - 173
  • [44] Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica
    El-Gamal, AAH
    Wang, SK
    Dai, CF
    Chen, IG
    Duh, CY
    JOURNAL OF NATURAL PRODUCTS, 2005, 68 (01): : 74 - 77
  • [45] A New 4α-Methylated Sterol from a Nephthea sp (Nephtheidae) Bornean Soft Coral
    Ishii, Takahiro
    Matsuura, Hiroshi
    Zhan Zhaoqi
    Vairappan, Charles Santhanaraju
    MOLECULES, 2009, 14 (09) : 3360 - 3366
  • [46] New Anti-Inflammatory Cembranes from the Cultured Soft Coral Nephthea columnaris
    Hsiao, Ting-Hsi
    Sung, Chun-Sung
    Lan, Yu-Hsuan
    Wang, Yi-Chen
    Lu, Mei-Chin
    Wen, Zhi-Hong
    Wu, Yang-Chang
    Sung, Ping-Jyun
    MARINE DRUGS, 2015, 13 (06): : 3443 - 3453
  • [47] Chabrolols A, B and C, three new norditerpenes from the soft coral Nephthea chabroli
    Zhang, WH
    Williams, ID
    Che, CT
    TETRAHEDRON LETTERS, 2001, 42 (28) : 4681 - 4685
  • [48] Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus
    Zhao, Yong
    Pu, Jian Xin
    Huang, Sheng Xiong
    Yang, Li Bin
    Xiao, Wei Lie
    Li, Li Mei
    Ding, Li Sheng
    Sun, Han Dong
    CHINESE CHEMICAL LETTERS, 2010, 21 (01) : 81 - 84
  • [49] Nardosinane sesquiterpenoids from the formosan soft coral Nephthea elongata
    Wang, Shang-Kwei
    Duh, Chang-Yih
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (05) : 762 - 765
  • [50] Prenylbicyclogermacrane diterpenoids from the Formosan soft coral Nephthea elongata
    El-Gamal, Ali Ali Hassan
    Wang, Shang-Kwei
    Duh, Chang-Yih
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (06) : 890 - 893