Impact of Micro- and Nanoplastics on Mitochondria

被引:33
|
作者
Lee, Seung Eun [1 ]
Yi, Yoojung [2 ]
Moon, Sangji [2 ]
Yoon, Hyunkyung [2 ]
Park, Yong Seek [1 ]
机构
[1] Kyung Hee Univ, Sch Med, Dept Microbiol, 26 Kyungheedae Gil, Seoul 02447, South Korea
[2] Kyung Hee Univ, Grad Sch, Dept Biomed Sci, Seoul 02447, South Korea
基金
新加坡国家研究基金会;
关键词
mitochondria; micro- and nanoplastics; environmental contaminants; toxicity; MICROPLASTICS; DNA; DYSFUNCTION; MUTATIONS; SIZE;
D O I
10.3390/metabo12100897
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mitochondria are highly dynamic cellular organelles that perform crucial functions such as respiration, energy production, metabolism, and cell fate decisions. Mitochondrial damage and dysfunction critically lead to the pathogenesis of various diseases including cancer, diabetes, and neurodegenerative and cardiovascular disorders. Mitochondrial damage in response to environmental contaminant exposure and its association with the pathogenesis of diseases has also been reported. Recently, persistent pollutants, such as micro- and nanoplastics, have become growing global environmental threats with potential health risks. In this review, we discuss the impact of micro- and nanoplastics on mitochondria and review current knowledge in this field.
引用
收藏
页数:10
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