DNA Molecular Logic Gates based on DNAzyme Regulation

被引:2
|
作者
Wu, Ranfeng [1 ]
Li, Yifan [1 ]
Yang, Jing [1 ]
机构
[1] North China Elect Power Univ, Sch Control & Comp Engn, Beijing 102206, Peoples R China
关键词
DNAzyme; logic gate; strand displacement; catalytic reaction; NANOTECHNOLOGY; COMPUTER; DEVICE; ACID;
D O I
10.1109/ICISCE.2017.206
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
With the advantages of strong parallelism and mass information storage, DNA computing has become the hot spot in the field of computer science, mathematic, and nanoscience. Using DNA computing, lots of complex problems have been solved. Compared with the logic gates based on DNA strand displacement, we present an optimize strategy to introduce DNAzyme as a control. The output of this system depends on the fluorescent signals obtained by DNAzyme cutting. Additionally, we introduce the catalytic mechanism to speed up the reaction. Using this method, more complex structures could be built in the future research. Our strategy offers a new way to manipulate and control logic gates, demonstrating great potential application in computing field.
引用
收藏
页码:975 / 978
页数:4
相关论文
共 50 条
  • [1] DNAzyme-Based Dissipative DNA Strand Displacement for Constructing Temporal Logic Gates
    Hu, Minghao
    Li, Xiaolong
    Wu, Jia-ni
    Yang, Mengyao
    Wu, Tongbo
    [J]. ACS NANO, 2024, 18 (03) : 2184 - 2194
  • [2] Colorimetric Logic Gates Based on Supramolecular DNAzyme Structures
    Bi, Sai
    Yan, Yameng
    Hao, Shuangyuan
    Zhang, Shusheng
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (26) : 4438 - 4442
  • [3] Integration of DNA-RNA-triplex-based regulation of transcription into molecular logic gates
    Rilievo, Graziano
    Cecconello, Alessandro
    Ghareshiran, Nima Fouladi
    Magro, Massimiliano
    Simmel, Friedrich C.
    Vianello, Fabio
    [J]. FEBS LETTERS, 2023, 597 (19) : 2461 - 2472
  • [4] Cascaded molecular logic gates using antibiotics as inputs based on exonuclease III and DNAzyme
    Deng, Fang
    Pan, Jiafeng
    Liu, Zhi
    Chen, Junhua
    [J]. TALANTA, 2023, 252
  • [5] Molecular logic gates based on localized DNA strand displacement
    Wang, Yanfeng
    Zhang, Wenwen
    Li, Xing
    Cui, Guangzhao
    [J]. Journal of Computational and Theoretical Nanoscience, 2016, 13 (06) : 3948 - 3952
  • [6] Designing logic gates based on 3-way DNAzyme complex
    Liu, Donglin
    Liu, Yuan
    Wang, Bin
    Zhang, Qiang
    [J]. ANALYTICAL METHODS, 2020, 12 (05) : 693 - 700
  • [7] Logic Gates Based on DNA Aptamers
    Andrianova, Mariia
    Kuznetsov, Alexander
    [J]. PHARMACEUTICALS, 2020, 13 (11) : 1 - 49
  • [8] Multivalued Logic Gates Based on DNA
    Pu, Fang
    Ren, Jinsong
    Yang, Xinjian
    Qu, Xiaogang
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (35) : 9590 - 9594
  • [9] Biosensors based on DNA logic gates
    Yin, Fangfei
    Wang, Fei
    Fan, Chunhai
    Zuo, Xiaolei
    Li, Qian
    [J]. VIEW, 2021, 2 (02)
  • [10] Logic reversibility and thermodynamic irreversibility demonstrated by DNAzyme-based Toffoli and Fredkin logic gates
    Orbach, Ron
    Remacle, Franoise
    Levine, R. D.
    Willner, Itamar
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (52) : 21228 - 21233