Emotional arousal regulation of memory consolidation

被引:61
|
作者
McGaugh, James L. [1 ]
机构
[1] Univ Calif Irvine, Dept Neurobiol & Behav, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA
关键词
INDUCED NORADRENERGIC ACTIVATION; AMYGDALA-HIPPOCAMPAL CONNECTIVITY; LONG-TERM-MEMORY; GLUCOCORTICOIDS INTERACT; ENHANCES CONSOLIDATION; ARC PROTEIN; MODULATION; EXPRESSION; RETRIEVAL; STRESS;
D O I
10.1016/j.cobeha.2017.10.003
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Recent findings provide increased understanding of how emotional arousal creates lasting memories. The findings are consistent with those of prior studies suggesting that the enhancement assessed in human subjects results from activation of adrenergic and glucocorticoid stress hormones. Additionally, fMRI imaging findings indicate that the enhancement is influenced by activation of the amygdala and its subsequent influences on other brain systems. Findings of recent animal studies using posttraining noradrenergic or optogenetic activation of the amygdala provide extensive evidence that the basolateral amygdala modulates memory consolidation by influencing neuroplasticity in downstream brain systems involved in processing different forms of memory. Activation of these systems helps to insure that emotionally significant experiences are well remembered.
引用
收藏
页码:55 / 60
页数:6
相关论文
共 50 条
  • [41] The effect of arousal on the emotional memory network depends on valence
    Steinmetz, Katherine R. Mickley
    Addis, Donna Rose
    Kensinger, Elizabeth A.
    [J]. NEUROIMAGE, 2010, 53 (01) : 318 - 324
  • [42] Influence of emotional valence and arousal on the spread of activation in memory
    Jhean-Larose, Sandra
    Leveau, Nicolas
    Denhiere, Guy
    [J]. COGNITIVE PROCESSING, 2014, 15 (04) : 515 - 522
  • [43] The effects of arousal and attention on emotional false memory formation
    Hellenthal, Maria V.
    Knott, Lauren M.
    Howe, Mark L.
    Wilkinson, Samantha
    Shah, Datin
    [J]. JOURNAL OF MEMORY AND LANGUAGE, 2019, 107 : 54 - 68
  • [44] A novel demonstration of enhanced memory associated with emotional arousal
    Cahill, L
    McGaugh, JL
    [J]. CONSCIOUSNESS AND COGNITION, 1995, 4 (04) : 410 - 421
  • [45] Emotional arousal does not enhance association-memory
    Madan, Christopher R.
    Caplan, Jeremy B.
    Lau, Christine S. M.
    Fujiwara, Esther
    [J]. JOURNAL OF MEMORY AND LANGUAGE, 2012, 66 (04) : 695 - 716
  • [46] Emotional arousal and multiple memory systems in the mammalian brain
    Packard, Mark G.
    Goodman, Jarid
    [J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2012, 6 : 1 - 38
  • [47] Predicting emotional arousal and emotional memory performance from an identical brain network
    Loos, Eva
    Egli, Tobias
    Coynel, David
    Fastenrath, Matthias
    Freytag, Virginie
    Papassotiropoulos, Andreas
    de Quervain, Dominique J-F
    Milnik, Annette
    [J]. NEUROIMAGE, 2019, 189 : 459 - 467
  • [48] INTERACTIONS BETWEEN TEMPERATURE REGULATION AND EMOTIONAL AROUSAL IN THE RABBIT
    FRANZINI, C
    LENZI, P
    CIANCI, T
    [J]. EXPERIMENTAL BRAIN RESEARCH, 1981, 43 (01) : 87 - 92
  • [49] Amygdala activation and the regulation of memory consolidation
    McGaugh, JL
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 2005, : 6 - 6
  • [50] Lasting increases in basolateral amygdala activity after emotional arousal:: Implications for facilitated consolidation of emotional memories
    Pelletier, JG
    Likhtik, E
    Filali, M
    Paré, D
    [J]. LEARNING & MEMORY, 2005, 12 (02) : 96 - 102