Discovery and characterization of new original blocking antibodies targeting the CD73 immune checkpoint for cancer immunotherapy

被引:4
|
作者
Paoli, Marc Giraudon
Augier, Severine
Blemont, Marilyne Royannez
Rodriguez, Celine
Blanc, Helene Rispaud
Chanteux, Stephanie
Gourdin, Nicolas
Gauthier, Laurent
Caux, Christine Menetrier
Morel, Yannis
Caux, Christophe
Paturel, Carine
Perrot, Ivan
机构
关键词
D O I
10.1158/1538-7445.AM2016-2344
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2344
引用
收藏
页数:3
相关论文
共 50 条
  • [31] Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR
    Ploeg, Emily Maria
    Samplonius, Douwe Freerk
    Xiong, Xiao
    Ke, Xiurong
    Hendriks, Mark Alexander Johannes Martinus
    Britsch, Isabel
    van Wijngaarden, Anne Paulien
    Zhang, Hao
    Helfrich, Wijnand
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (09)
  • [32] Predictive value of CD73 expression for the efficacy of immune checkpoint inhibitors in NSCLC
    Ishii, Hidenobu
    Azuma, Koichi
    Kawahara, Akihiko
    Kinoshita, Takashi
    Matsuo, Norikazu
    Naito, Yoshiko
    Tokito, Takaaki
    Yamada, Kazuhiko
    Akiba, Jun
    Hoshino, Tomoaki
    THORACIC CANCER, 2020, 11 (04) : 950 - 955
  • [33] Cancer immunotherapy by targeting immune checkpoint receptors
    Noah Isakov
    World Journal of Immunology, 2018, (01) : 1 - 11
  • [34] A differentiated CD73 blocking antibody with a unique intra-dimer binding mechanism for cancer immunotherapy.
    Wang, Zhengyi
    Cao, Wei
    Zhang, Yanni
    Xu, Cong
    Meng, Yuan
    Guo, Taylor B.
    CANCER RESEARCH, 2021, 81 (13)
  • [36] Investigation of CD73 expression in response to immunotherapy in pan-cancer
    Wang, Y.
    Liu, M.
    Hu, X.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S893 - S893
  • [37] CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment
    Neo, Shi Yong
    Yang, Ying
    Record, Julien
    Ma, Ran
    Chen, Xinsong
    Chen, Ziqing
    Tobin, Nicholas P.
    Blake, Emily
    Seitz, Christina
    Thomas, Ron
    Wagner, Arnika Kathleen
    Andersson, John
    de Boniface, Jana
    Bergh, Jonas
    Murray, Shannon
    Alici, Evren
    Childs, Richard
    Johansson, Martin
    Westerberg, Lisa S.
    Haglund, Felix
    Hartman, Johan
    Lundqvist, Andreas
    JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (03): : 1185 - 1198
  • [38] A Novel Bispecific Antibody for EpCAM-Directed Inhibition of the CD73/Adenosine Immune Checkpoint in Ovarian Cancer
    Ploeg, Emily Maria
    Britsch, Isabel
    van Wijngaarden, Anne Paulien
    Ke, Xiurong
    Hendriks, Mark Alexander Johannes Martinus
    Samplonius, Douwe Freerk
    Helfrich, Wijnand
    CANCERS, 2023, 15 (14)
  • [39] CD39/CD73/A2AR pathway and cancer immunotherapy
    Xia, Chenglai
    Yin, Shuanghong
    To, Kenneth K. W.
    Fu, Liwu
    MOLECULAR CANCER, 2023, 22 (01)
  • [40] CD39/CD73/A2AR pathway and cancer immunotherapy
    Chenglai Xia
    Shuanghong Yin
    Kenneth K. W. To
    Liwu Fu
    Molecular Cancer, 22