Preparation, characterization and antioxidant activity of polysaccharide from Fallopia multiflora (Thunb.) Harald

被引:15
|
作者
Chen, Li [1 ,3 ,4 ]
Zhang, Yipeng [2 ]
Jin, Lixin [1 ,3 ,4 ]
Gao, Renjiao [1 ,3 ,4 ]
Bao, Jiaqi [1 ,3 ,4 ]
Cui, Bowen [1 ,3 ,4 ]
机构
[1] Huaihai Inst Technol, Jiangsu Marine Resources Dev Res Inst, 59 Cangwu Rd, Haizhou 222005, Peoples R China
[2] Dalian Univ Technol, Sch Chem Engn, 2 Linggong Rd, Dalian 116024, Peoples R China
[3] Huaihai Inst Technol, Jiangsu Key Lab Marine Pharmaceut Compound Screen, Haizhou 222005, Peoples R China
[4] Huaihai Inst Technol, Coinnovat Ctr Jiangsu Marine Bioind Technol, Lianyungang 222005, Peoples R China
关键词
Fallopia multiflora; Polysaccharide; Antioxidant activities; IN-VITRO; ANTIBACTERIAL; EXTRACTS; DAMAGE; VIVO;
D O I
10.1016/j.ijbiomac.2017.12.020
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This study aimed to investigate antioxidant activities of a polysaccharide from Fallopia multiflora (Thunb.) Harald. F. multiflora polysaccharide (FMP) was prepared and partially characterized by high performance liquid chromatography, fourier transform infrared spectrum and anion chromatography, and its antioxidant activities both in vitro and in vivo were investigated. FMP, with a molecular weight of 17,758 Da consisted of glucose. In vivo, FMP had high hydroxyl radical scavenging activity and reducing capacity. In vivo, FMP increased serum superoxide dismutase and glutathione peroxidise activities and decreased the level of malondialdehyde. These results indicated that FMP exhibits high antioxidant activity both in vitro and in vivo and might retard human ageing associated with free radicals. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:259 / 262
页数:4
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