Magnetic Bioactive SrFe12O19-SiO2-CaO-Na2O-P2O5 Glass-Ceramics for Hyperthermia Treatment of Bone Cancer

被引:11
|
作者
Leenakul, W. [1 ]
Intawin, P. [1 ]
Ruangsuriya, J. [2 ]
Jantaratana, P. [3 ]
Pengpat, K. [1 ]
机构
[1] Chiang Mai Univ, Fac Sci, Dept Phys & Mat Sci, Chiang Mai 50200, Thailand
[2] Chiang Mai Univ, Dept Biochem, Fac Med, Chiang Mai 50200, Thailand
[3] Kasetsart Univ, Dept Phys, Magnet Mat Special Res Unit, Fac Sci, Bangkok 10900, Thailand
关键词
45S5; bioglass; ferrimagnetic; solid-state sintering; biocompatibility;
D O I
10.1080/10584587.2013.852034
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The magnetic bioglass-ceramics were introduced for hyperthermia treatment of bone cancer. The aim of this work was to study the magnetic properties of ferrimagnetic glass-ceramics from SrFe12O19(SF)-SiO2-CaO-Na2O-P2O5 system by using the modified solid-state sintering method. The results showed that sodium calcium silicate (Na4Ca4Si6O18), strontium iron oxide (SrFe12O19) and iron oxide (Fe2O3) were precipitated in all samples. The saturation magnetization (M-s), remanence (M-r) and coercivity (H-c) increased by the addition of SF in the bioglass. The samples were soaked in simulated body fluid (SBF) for 14days in order to investigate the bioactivity of the samples in vitro. The apatite layer was found on the surface of all bioglass-ceramics confirming their biocompatibility and it increased with increasing strontium ferrite content.
引用
收藏
页码:81 / 89
页数:9
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