A review on liposomal drug delivery system

被引:0
|
作者
Muralikrishnan, R. [1 ]
Selvamuthukumar, R. [1 ]
Mohankumar, A. [1 ]
Praveen, K. [1 ]
Swamivelmanickam, M. [1 ]
Sivakrishnan, S. [1 ]
机构
[1] Annamalai Univ, Dept Pharm, Chidambaram, Tamil Nadu, India
来源
RESEARCH JOURNAL OF BIOTECHNOLOGY | 2020年 / 15卷 / 08期
关键词
Liposomes; Pharmacokinetics; Intracellular Compartments; Drug Delivery; PHOSPHOLIPIDS; MICROENCAPSULATION; TOXICITY;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Liposomes are microparticulate created from lipoidal vesicles. It absolutely was used as drug carriers in enhancing the delivery of therapeutic agents. Liposomes, that are perishable and necessary nontoxic vesicles, will encapsulate each deliquescent and lipotropic medicine and yet maintain them from the external condition that end up in degradation. Several liposomes based mostly drug strategies are within the trial, and that they are approved for clinical use. Liposome may be target on the tissues, cells and animate thing compartments with or blankly of target recognition on liposome membrane. The grouping of liposome provides an opportunity to reinforce the therapeutic index of assorted dynamic medicine by ever changing their pharmacokinetic and pharmacodynamics parameters. The success of liposome as drug carriers is seen within the range of liposome formulation which are commercially there in the market. During this review, we tend to discuss the mechanism of liposome formation, methods of preparation, classification of the liposome, evaluation of liposome, their applications and marketed products.
引用
收藏
页码:124 / 135
页数:12
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