Effects of cold atmospheric pressure plasma and disinfecting agents onCandida albicansin root canals of extracted human teeth

被引:11
|
作者
Kerlikowski, Anne [1 ]
Matthes, Rutger [1 ]
Pink, Christiane [1 ]
Steffen, Heike [1 ]
Schluter, Rabea [2 ]
Holtfreter, Birte [1 ]
Weltmann, Klaus-Dieter [3 ]
von Woedtke, Thomas [3 ,4 ]
Kocher, Thomas [1 ]
Jablonowski, Lukasz [1 ]
机构
[1] Univ Med Greifswald, Dent Sch, Dept Restorat Dent Periodontol Endodontol Prevent, Rotgerberstr 8, D-17475 Greifswald, Germany
[2] Ernst Moritz Arndt Univ Greifswald, Dept Biol, Imaging Ctr, Greifswald, Germany
[3] Leibniz Inst Plasma Sci & Technol eV, Dept Plasma Life Sci, Greifswald, Germany
[4] Univ Med Greifswald, Dept Hyg & Environm Med, Greifswald, Germany
关键词
Candida albicans; cold atmospheric pressure plasma; human teeth; medical plasma; root canal; CANDIDA-ALBICANS; ENDODONTIC TREATMENT; IN-VITRO; INACTIVATION; BIOFILMS; THERAPY; FAECALIS;
D O I
10.1002/jbio.202000221
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Reinfection in endodontically treated teeth is linked to the complexity of the root canal system, which is problematic to reach with conventional disinfection methods. As plasma is expected to have the ability to sanitize narrow areas, the aim of this study was to analyze the effect of cold atmospheric pressure plasma (CAP) onCandida albicansin root canals of extracted human teeth. CAP was applied as mono treatment and in combination with standard endodontic disinfectants (sodium hypochlorite, chlorhexidine and octenidine). Disinfection efficiency was evaluated as reduction of the logarithm of colony forming units per milliliter (log(10)CFU/mL) supported by scanning electron microscopy as imaging technique. Plasma alone showed the highest reduction of log(10)CFU, suggesting the best disinfection properties of all tested agents.
引用
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页数:9
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