A highly specific BODIPY-based probe localized in mitochondria for HClO imaging

被引：173

作者：

Cheng, Guanghui ^{[1
]}

Fan, Jiangli ^{[1
]}

Sun, Wen ^{[1
]}

Sui, Kun ^{[1
]}

Jin, Xin ^{[1
]}

Wang, Jingyun ^{[2
]}

Peng, Xiaojun ^{[1
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China

[2] Dalian Univ Technol, Sch Life Sci & Biotechnol, Dalian 116024, Peoples R China

来源：

ANALYST | 2013年 / 138卷 / 20期

基金：

国家高技术研究发展计划(863计划);

关键词：

2-PHOTON FLUORESCENT-PROBE; HYPOCHLOROUS ACID; REACTIVE OXYGEN; MYELOPEROXIDASE; DERIVATIVES; OXIDATION; SENSOR; DNA;

D O I：

10.1039/c3an01152f

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An oxime containing fluorescent probe based on a BODIPY scaffold was successfully designed and used for HClO determination with rapid response, low detection limits and high selectivity. Confocal fluorescence microscopy demonstrated that the probe could permeate the mitochondria and made possible the fast fluorescent imaging of endogenous HClO.

引用

页码：6091 / 6096

页数：6

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