An efficient method for Knoevenagel condensation: a facile synthesis of 5-arylidenyl 2,4-thiazolidinedione

被引:41
|
作者
Mahalle, Shital R. [1 ]
Netankar, Prashant D. [1 ]
Bondge, Sandipan P. [1 ]
Mane, Ramrao A. [1 ]
机构
[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad, Maharashtra, India
关键词
5-arylidenyl 2,4-thiazolidinedione; 2,4-thiazolidinedione; Knoevenagel condensation; polyethylene glycol (PEG-300);
D O I
10.1080/17518250802139881
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione has been carried out in polyethylene glycol-300. The reactions were carried out at moderate temperature with very simple isolation procedure and with better yields.
引用
收藏
页码:103 / 106
页数:4
相关论文
共 50 条
  • [41] Synthesis of 5-arylidene-2,4-thiazolidinediones by Knoevenagel condensation catalyzed by baker's yeast
    Pratap, Umesh R.
    Jawale, Dhanaji V.
    Waghmare, Rahul A.
    Lingampalle, Dinesh L.
    Mane, Ramrao A.
    NEW JOURNAL OF CHEMISTRY, 2011, 35 (01) : 49 - 51
  • [42] STUDIES ON ANTIDIABETIC AGENTS .4. SYNTHESIS AND ACTIVITY OF THE METABOLITES OF 5-[4-(1-METHYLCYCLOHEXYLMETHOXY)BENZYL]-2,4-THIAZOLIDINEDIONE (CIGLITAZONE)
    SOHDA, T
    MEGURO, K
    KAWAMATSU, Y
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1984, 32 (06) : 2267 - 2278
  • [43] Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein
    Budassi, Federica
    Marchioro, Chiara
    Canton, Martina
    Favaro, Annagiulia
    Sturlese, Mattia
    Urbinati, Chiara
    Rusnati, Marco
    Romagnoli, Romeo
    Viola, Giampietro
    Mariotto, Elena
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 261
  • [44] Synthesis of new chalcone derivatives bearing 2,4-thiazolidinedione and benzoic acid moieties as potential anti-bacterial agents
    Liu, Xiao-Fang
    Zheng, Chang-Ji
    Sun, Liang-Peng
    Liu, Xue-Kun
    Piao, Hu-Ri
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (08) : 3469 - 3473
  • [45] Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR- modulators
    Naim, Mohd Javed
    Alam, Ozair
    Alam, Md Jahangir
    Shaquiquzzaman, Mohammad
    Alam, Md Mumtaz
    Naidu, Vegi Ganga Modi
    ARCHIV DER PHARMAZIE, 2018, 351 (3-4)
  • [46] 2,4-Thiazolidinedione in Well-Fed Lactating Dairy Goats: I. Effect on Adiposity and Milk Fat Synthesis
    Jaaf, Shana
    Rosa, Fernanda
    Moridi, Misagh
    Osorio, Johan S.
    Lohakare, Jayant
    Trevisi, Erminio
    Filley, Shelby
    Cherian, Gita
    Estill, Charles T.
    Bionaz, Massimo
    VETERINARY SCIENCES, 2019, 6 (02)
  • [47] Studies on antidiabetic agents .12. Synthesis and activity of the metabolites of (+/-)-5-[p-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione (pioglitazone)
    Sohda, T
    Ikeda, H
    Meguro, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1995, 43 (12) : 2168 - 2172
  • [48] A facile method for synthesis of amine-functionalized mesoporous zirconia and its catalytic evaluation in Knoevenagel condensation
    Parida, K. M.
    Mallick, Sujata
    Sahoo, P. C.
    Rana, S. K.
    APPLIED CATALYSIS A-GENERAL, 2010, 381 (1-2) : 226 - 232
  • [49] Facile synthesis of 2-fluoroindenones via a Knoevenagel condensation/palladium-catalyzed annulation
    Su, Yue
    Fang, Xiang
    Zhou, Jun
    Bian, Yizhen
    Yang, Xueyan
    Wu, Fanhong
    JOURNAL OF FLUORINE CHEMISTRY, 2018, 211 : 76 - 80
  • [50] Microwave assisted Knoevenagel condensation: A facile method for the synthesis of 5-arylidine barbituric acid derivatives under solvent free conditions
    Pandit, S. S.
    Jejurkar, B. N.
    Harde, R. L.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2007, 84 (10) : 1035 - 1036