Cutaneous Changes: An Initial Manifestation of Pulmonary Wegener's Granulomatosis

被引：12

作者：

Zycinska, Katarzyna ^{[1
,2
]}

Wardyn, Kazimierz ^{[1
,2
]}

Zielonka, Tadeusz M. ^{[1
,2
]}

Nitsch-Osuch, Aneta ^{[1
,2
]}

Smolarczyk, Roman ^{[1
,2
]}

机构：

[1] Med Univ Warsaw, Dept Family Med, PL-02097 Warsaw, Poland

[2] Czerniakowski Hosp Warsaw, Syst Vasculitis Outpatient Clin, Warsaw, Poland

来源：

RESPIRATORY REGULATION - CLINICAL ADVANCES | 2013年 / 755卷

关键词：

Wegener's granulomatosis; Pyoderma gangrenosum; Skin biopsy; Cutaneous vasculitis; Leukocytoclastic vasculitis; VASCULITIS UPDATE; SKIN;

D O I：

10.1007/978-94-007-4546-9_39

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Cutaneous vasculitis can occur as an isolated dermatologic disorder or as manifestation of a potentially life-threatening systemic vasculitis such as Wegener's granulomatosis (WG). The aim of the study was to characterize cutaneous lesions in 66 WG patients (30 female, 36 male) and to assess the viability of skin biopsy the diagnosis of WG. Skin involvement was observed in 21 (32%) WG patients; in 14 (21%) patients as an initial manifestation and in other seven during the diagnosis establishment. Cutaneous lesions included palpable purpura (n = 10), subcutaneous nodules (n = 4), hemorrhagic bullae (n = 3), ulcers (n = 2), pustules (n = 1), pyoderma gangrenosum (n = 1). The patient with pulmonary WG can present initially with cutaneous symptoms and positive PR3-ANCA serologic test results. Leukocytoclastic vasculitis (LCV) was the predominant histopathologic pattern.

引用

页码：307 / 310

页数：4

共 50 条

[21] Pachymeningitis as a presenting manifestation of Wegener's granulomatosis
Hota, D.
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2019, 405
[22] Horner's syndrome as manifestation of Wegener's granulomatosis
O Weijtens
N Mooy
D Paridaens
Eye, 2004, 18 : 846 - 848
[23] Otologic Symptoms as Initial Manifestation of Wegener Granulomatosis: Diagnostic Dilemma
Wierzbicka, Malgorzata
Szyfter, Witold
Puszczewicz, Mariusz
Borucki, Lukasz
Bartochowska, Anna
OTOLOGY & NEUROTOLOGY, 2011, 32 (06) : 996 - 1000
[24] Cutaneous Manifestation of Kikuchi-Fujimoto Disease in the Setting of Granulomatosis with Polyangiitis (Wegener's)
DeFilipp, Zachariah
JOURNAL OF GENERAL INTERNAL MEDICINE, 2012, 27 (09) : 1220 - 1222
[25] Subglottic stenosis as the initial manifestation of Wegener's granulomatosis in a teenager. Case report
Cuestas, Giselle
Rodriguez, Veronica
Doormann, Flavia
Pringe, Alejandra
Bellia Munzon, Patricio
Bellia Munzon, Gaston
Ortega, Carlos
Alvareze, Ruben
ARCHIVOS ARGENTINOS DE PEDIATRIA, 2017, 115 (02): : E120 - E125
[26] Orbital tumor as an initial manifestation of Wegener's granulomatosis in children: A series of four cases
Chipczynska, Barbara
Gralek, Miroslawa
Hautz, Wojciech
Zegadlo-Mylik, Maria
Kocyla-Karczmarewicz, Beata
Kanigowska, Krystyna
Kepa, Beata
Seroczynska, Malgorzata
Klimczak-Slaczka, Dorota
MEDICAL SCIENCE MONITOR, 2009, 15 (08): : CS135 - CS138
[27] Pulmonary cavernae in Wegener's granulomatosis
Schwenger, V
Morath, C
Kihm, LP
Andrassy, K
Zeier, M
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2006, 21 (03) : 818 - 818
[28] Role of gingival manifestation in diagnosis of granulomatosis with polyangiitis (Wegener's granulomatosis)
Sung, Iel-Yong
Kim, Young-Min
Cho, Yeong-Cheol
Son, Jang-Ho
JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, 2015, 45 (06): : 247 - 251
[29] Gingival granulomatosis with polyangiitis (Wegener's granulomatosis) as a primary manifestation of the disease
Fonseca, F. P.
Benites, B. M.
Ferrari, A. L. V.
Sachetto, Z.
de Campos, G. V.
de Almeida, O. P.
Fregnani, E. R.
AUSTRALIAN DENTAL JOURNAL, 2017, 62 (01) : 102 - 106
[30] Xanthogranuloma of the lacrimal sac as a manifestation of Wegener's granulomatosis
Fernandes, B. F.
Al-Kandari, A.
Al-Mujaini, A.
Codere, F.
Burnier, M. N., Jr.
EYE, 2007, 21 (02) : 260 - 262

← 1 2 3 4 5 →