Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

被引：20
|
作者：
Kotipalli, Trimurtulu [1 ]
Kavala, Veerababurao [1 ]
Janreddy, Donala [1 ]
Kuo, Chun-Wei [1 ]
Kuo, Ting-Shen [1 ]
Huang, Hsiu-Ni [1 ]
He, Chiu-Hui [1 ]
Yao, Ching-Fa [1 ]
机构：
[1] Natl Taiwan Normal Univ, Dept Chem, Taipei 116, Taiwan
来源：
RSC ADVANCES | 2014年 / 4卷 / 05期
关键词：
ONE-POT SYNTHESIS; N-ARYLATION; COUPLING REACTIONS; CYCLIZATION; EFFICIENT; ARYL; HALIDES; TRYPTANTHRIN; ANALOGS; CASCADE;
D O I：
10.1039/c3ra44798g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.
引用
收藏
页码：2274 / 2283
页数：10
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