Dual Kidney Transplant: A Single-Center Experience and Review of the Literature

被引:7
|
作者
Balaz, Peter [1 ]
Rokosny, Slavomir [1 ]
Wohlfahrt, Peter [2 ,3 ,4 ,5 ]
Wohlfahrtova, Mariana [6 ]
Adamec, Milos [1 ]
Janousek, Libor [1 ]
Fronek, Jiri [1 ]
Viklicky, Ondrej [6 ]
Pokorna, Eva [7 ]
机构
[1] Inst Clin & Expt Med, Dept Surg, Prague 14021, Czech Republic
[2] Inst Clin & Expt Med, Dept Prevent Cardiol, Prague 14021, Czech Republic
[3] Charles Univ Prague, Fac Med 1, Ctr Cardiovasc Prevent, Prague, Czech Republic
[4] Thomayer Hosp, Prague, Czech Republic
[5] St Annes Univ Hosp, Int Clin Res Ctr, Brno, Czech Republic
[6] Inst Clin & Expt Med, Dept Nephrol, Prague 14021, Czech Republic
[7] Inst Clin & Expt Med, Transplantctr, Prague 14021, Czech Republic
关键词
Dual kidney transplant; Elderly donors; Expanded criteria donors; EXPANDED CRITERIA DONORS; RENAL-TRANSPLANTATION; MARGINAL DONORS; GRAFT-SURVIVAL; IMMUNOSUPPRESSION; ALLOCATION; ALLOGRAFTS; RECIPIENTS; ORGANS; POOL;
D O I
10.6002/ect.2013.0040
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Objectives: Adult dual kidney transplant is a strategy to overcome the imbalance between limited nephron mass supplied from an older donor and a recipient with a metabolic request. Materials and Methods: In our report, we review the literature and present our single-center experience. From June 2007 until July 2012, nine hundred twenty-eight single and seventeen dual kidney transplants from deceased donors were performed. Results: The average donor was 71.5 +/- 3.6 years of age with an average serum creatinine, creatinine clearance, and an average number of sclerotic glomeruli, 106.1 +/- 44.2 mu mol/L, 0.97 +/- 0.37 mL/s, and 22.4 +/- 14.2. Immediate graft function and acute rejection episodes were observed in 75% and 6% of patients. The overall patient survival rates at 1 and 2 years after transplant were 93%. The overall graft survival rates at 1 and 2 years were 88%. Conclusions: Previous studies and our single-center experience suggest that the dual transplant procedure may help improve results of kidney transplants from expanded criteria donors and extend the donor pool by using kidneys that would be discarded otherwise.
引用
收藏
页码:388 / 395
页数:8
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