Inhibition of AKT/mTOR signaling pathway induces cell cycle arrest and apoptosis in acute myelogenous leukemia.

被引：3
|
作者：
Chen, WN [1 ]
Grammatikakis, I [1 ]
Li, J [1 ]
Leventaki, V [1 ]
Medeiros, LJ [1 ]
Rassidakis, GZ [1 ]
机构：
[1] Univ Texas, MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA
来源：
BLOOD | 2005年 / 106卷 / 11期
关键词：
D O I：
10.1182/blood.V106.11.2355.2355
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2355
引用
收藏
页码：663A / 663A
页数：1
相关论文
共 50 条
  • [41] Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway
    Yang, Jing
    Zhu, Xin-jiang
    Jin, Ming-zhu
    Cao, Zhi-wei
    Ren, Yao-yao
    Gu, Zhao-wei
    [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 2020, 316
  • [42] CHOLESTEROL SYNTHESIS INHIBITION INDUCES LEUKEMIA-SPECIFIC CYTOPROTECTIVE AUTOPHAGY VIA SUPPRESSION OF THE AKT/MTOR SIGNALING PATHWAY
    Bosnjak, M.
    Bogdanovic, A.
    Markovic, I.
    Isakovic, A.
    Trajkovic, V.
    Bumbasirevic, V.
    Vilimanovich, U.
    [J]. HAEMATOLOGICA, 2013, 98 : 675 - 675
  • [43] Berberine Induces Autophagic Cell Death by Inactivating the Akt/mTOR Signaling Pathway
    Park, Gil-Sun
    Park, Bokyung
    Lee, Mi-Young
    [J]. PLANTA MEDICA, 2022, 88 (13) : 1116 - 1122
  • [44] Isoliensinine induces cervical cancer cell cycle arrest and apoptosis by inhibiting the AKT/GSK3α pathway
    Li, Hong-Li
    Cheng, Yan
    Zhou, Zi-Wei
    Long, Hui-Zhi
    Luo, Hong-Yu
    Wen, Dan-Dan
    Cheng, Lin
    Gao, Li-Chen
    [J]. ONCOLOGY LETTERS, 2022, 23 (01)
  • [45] Combination of cytokinin and auxin induces apoptosis, cell cycle progression arrest and blockage of the Akt pathway in HeLa cells
    Zhao, Liwei
    Liu, Peng
    Guo, Guangqin
    Wang, Li
    [J]. MOLECULAR MEDICINE REPORTS, 2015, 12 (01) : 719 - 727
  • [46] Plumbagin induces Ishikawa cell cycle arrest, autophagy, and apoptosis via the PI3K/Akt signaling pathway in endometrial cancer
    Zhang, Xiangsheng
    Kan, Huan
    Liu, Yun
    Ding, Wu
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2021, 148
  • [47] Biologic effects of curcumin on apoptosis in acute and chronic myelogenous leukemia.
    Kim, JS
    Bae, EK
    Ahn, KS
    Yoon, SS
    Park, S
    Kim, BK
    Kim, NK
    [J]. BLOOD, 2003, 102 (11) : 238B - 238B
  • [48] Chabamide induces cell cycle arrest and apoptosis by the Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells
    Ren, Jie
    Xu, Yuanyuan
    Huang, Qianhui
    Yang, Jie
    Yang, Meng
    Hu, Kun
    Wei, Kun
    [J]. ANTI-CANCER DRUGS, 2015, 26 (05) : 498 - 507
  • [49] Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia
    Chen, Taylor J.
    Shen, Ye
    Bridges, Cory Seth
    Park, Chun Shik
    Junco, Jacob J.
    Rabin, Karen R.
    Lacorazza, H. Daniel
    [J]. BLOOD, 2019, 134
  • [50] Safflower polysaccharide induces NSCLC cell apoptosis by inhibition of the Akt pathway
    Li, Jian-Ying
    Yu, Jun
    Du, Xu-Sheng
    Zhang, Hui-Min
    Wang, Bo
    Guo, Hua
    Bai, Jie
    Wang, Juan-Hong
    Liu, An
    Wang, Yi-Li
    [J]. ONCOLOGY REPORTS, 2016, 36 (01) : 147 - 154
12345