High expression of CD59 and CD55 on benign and malignant plasma cells

被引:12
|
作者
Alcindor, T
Kimlinger, T
Witzig, TE
机构
[1] McGill Univ, Dept Oncol, Montreal, PQ H3A 2T5, Canada
[2] McGill Univ, Dept Med, Div Med Oncol, Montreal, PQ H3A 2T5, Canada
[3] Mayo Clin & Mayo Fdn, Dept Internal Med, Rochester, MN 55905 USA
[4] Mayo Clin & Mayo Fdn, Div Hematol, Rochester, MN 55905 USA
关键词
D O I
10.1080/10428190500467784
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In summary, our study reveals a relatively high expression of complement regulatory proteins on the surface of plasma cells, which appears to be a constitutive feature of these cells, rather than a specific change induced by a malignant state. Further efforts will aim at establishing a correlation between CD55 and CD59 expression levels and in vitro and in vivo resistance to rituximab. © 2006 Taylor & Francis.
引用
收藏
页码:919 / 921
页数:3
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